Guiding Fibroblast Activation Using an RGD-Mutated Heparin Binding II Fragment of Fibronectin for Gingival Titanium Integration.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203307
Abstract: The formation of a biological seal around the neck of titanium (Ti) implants is critical for ensuring integration at the gingival site and for preventing bacterial colonization that may lead to periimplantitis. This process is… read more here.
Keywords: fibronectin; rgd; integration; heparin binding ... See more keywords
Photoswitchable Microgels for Dynamic Macrophage Modulation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205498
Abstract: Dynamic manipulation of supramolecular self‐assembled structures is achieved irreversibly or under non‐physiological conditions, thereby limiting their biomedical, environmental, and catalysis applicability. In this study, microgels composed of azobenzene derivatives stacked via π–cation and π–π interactions… read more here.
Keywords: rgd; rgd bearing; visible light; photoswitchable microgels ... See more keywords
Arsenic trioxide and Erlotinib loaded in RGD‐modified nanoliposomes for targeted combination delivery to PC3 and PANC‐1 cell lines
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2401
Abstract: During the past few years, advances in drag delivery have provided many opportunities in the treatment of various diseases and cancer. Arsenic trioxide (ATO) and Erlotinib (Erlo) are two drugs, approved by the United States… read more here.
Keywords: cell; rgd; erlo; ato erlo ... See more keywords
PAMAM G4.5 dendrimers for targeted delivery of ferulic acid and paclitaxel to overcome P‐glycoprotein‐mediated multidrug resistance
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27645
Abstract: In this study, we prepared ferulic acid (FA) and paclitaxel (PTX) co‐loaded polyamidoamine (PAMAM) dendrimers conjugated with arginyl–glycyl–aspartic acid (RGD) to overcome P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR). FA was released in greater extent (80%) from… read more here.
Keywords: pamam; ferulic acid; rgd; acid paclitaxel ... See more keywords
Binding stability of peptides to Co–Cr–Mo alloy affects proliferation and differentiation of osteoblast
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28041
Abstract: Cobalt–chromium–molybdenum (CCM) alloys possess high corrosion‐resistant properties as well as good mechanical properties. Hence, the alloys are employed in medical implants such as artificial knee and hip joints, coronary stents, and removable partial dentures. To… read more here.
Keywords: rgd; rgd adsorbed; cbp rgd; adsorbed alloy ... See more keywords
Synthesis of Functionalized Triblock Copolyesters Derived from Lactic Acid and Macrolactones for Bone Tissue Regeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300066
Abstract: Synthetic and functional grafts are a great alternative to conventional grafts. They can provide a physical support and the precise signaling for cells to heal damaged tissues. In this study, a novel RGD peptide end-functionalized… read more here.
Keywords: pla; rgd; pgl; lactic acid ... See more keywords
Interaction Mechanism and Clustering among RGD Peptides and Integrins
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Informatics"
DOI: 10.1002/minf.201600069
Abstract: Peptides with an exposed arginine–glycine–aspartate (Arg–Gly–Asp, RGD) sequence targeting the integrin αVβ3 play an important role in targeted anticancer drug delivery. The interaction of multiple RGD‐containing peptides and two αVβ3 molecules was studied via MD… read more here.
Keywords: rgd containing; interaction mechanism; interaction; containing peptides ... See more keywords
Conjugates of Cryptophycin and RGD or isoDGR Peptidomimetics for Targeted Drug Delivery
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DOI: 10.1002/open.201900110
Abstract: Abstract RGD‐cryptophycin and isoDGR‐cryptophycin conjugates were synthetized by combining peptidomimetic integrin ligands and cryptophycin, a highly potent tubulin‐binding antimitotic agent across lysosomally cleavable Val‐Ala or uncleavable linkers. The conjugates were able to effectively inhibit binding… read more here.
Keywords: conjugates cryptophycin; drug delivery; drug; isodgr ... See more keywords
Pre-culture of Mesenchymal Stem Cells within RGD-modified Hyaluronic Acid Hydrogel Improves their Resilience to Ischaemic Conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.02.043
Abstract: The incorporation of the RGD peptide (arginine-glycine-aspartate) into biomaterials has been proposed to promote cell adhesion to the matrix, which can influence and control cell behaviour and function. While many studies have utilised RGD modified… read more here.
Keywords: adhesion; hyaluronic acid; rgd modified; rgd ... See more keywords
Improved human islets' viability and functionality with mesenchymal stem cells and arg-gly-asp tripeptides supplementation of alginate micro-encapsulated islets in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.107
Abstract: INTRODUCTION The extension of islet transplantation to a wider number of type 1 diabetes patients is compromised by severe adverse events related to the immunosuppressant therapy required for allogenic islet transplantation. In this context, microencapsulation… read more here.
Keywords: functionality; viability functionality; rgd; rich alginate ... See more keywords
Synthesis of RGD-peptide modified poly(ester-urethane) urea electrospun nanofibers as a potential application for vascular tissue engineering
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2016.12.134
Abstract: Abstract The development of a biomimetic surface which is able to promote endothelialization is fundamental in the research for blood vessel substitutes to overcome the formation of thrombi or hyperplasia. In the present work, the… read more here.
Keywords: engineering; peuu; ester urethane; poly ester ... See more keywords