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Rat Group IIA Secreted Phospholipase A2 Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer’s Disease

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232012368

Abstract: Alzheimer’s disease (AD), a progressive form of dementia, is characterized by the increased expression of secreted phospholipase A2 group IIA (GIIA) in the affected tissue and the dysfunction of neuronal mitochondria, similar to that induced… read more here.

Keywords: secreted phospholipase; atx; rat; alzheimer disease ... See more keywords