Glycogen-based pH and redox sensitive nanoparticles with ginsenoside Rh2 for effective treatment of ulcerative colitis
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.121077
Abstract: Abstract The purpose of this study is to construct a pH and redox sensitive nanoparticle to effectively deliver ginsenoside Rh2 for the treatment of ulcerative colitis (UC). Herein, glycogen was modified by urocanic acid and… read more here.
Keywords: rh2 nps; rh2; redox sensitive; ulcerative colitis ... See more keywords
Construction of Ginsenosides nanoparticles with pH/reduction dual response for enhancement of its cytotoxicity towards HepG2 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c03698
Abstract: The aim of this study is to construct a pH and reduction responsive nanodrug delivery system to effectively deliver ginsenoside (Rh2) and enhance its cytotoxicity against human hepatocarcinoma cells (HepG2). Here, pullulan polysaccharide was grafted… read more here.
Keywords: rh2 nps; rh2; dual response; cytotoxicity ... See more keywords