Giant Pediatric Rhabdoid Meningioma Associated with a Germline BAP1 Pathogenic Variation: A Rare Clinical Case.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.06.227
Abstract: BACKGROUND Rhabdoid meningiomas are rare World Health Organization grade 3 tumors that tend to follow an aggressive course, with an increased likelihood for local recurrence, remote metastasis, and cerebrospinal fluid dissemination. Genetic testing has found… read more here.
Keywords: grade; bap1; rhabdoid; rhabdoid meningioma ... See more keywords
No compelling need to reclassify
Sign Up to like & getrecommendations! Published in 2017 at "Modern Pathology"
DOI: 10.1038/modpathol.2016.216
Abstract: To the Editor: Malignant rhabdoid tumor (MRT), regardless of its primary site, is one of the most aggressive and least therapeutically responsive neoplasms of childhood.1 The study by Kohashi et al proposes to remake the… read more here.
Keywords: mrt; type tumors; compelling need; need reclassify ... See more keywords
ATRT-22. HIGH-THROUGHPUT DRUG SCREENING OF FDA-APPROVED CANCER DRUGS REVEALS POTENTIAL THERAPEUTIC APPROACHES FOR ATYPICAL TERATOID RHABDOID TUMOUR
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.021
Abstract: Abstract Atypical teratoid/rhabdoid tumors (ATRT), are the most common brain tumor in children under the age of 1 year with an overall survival of ~17%. Like extracranial rhabdoid tumors, ATRT is exclusively characterized by bi-allelic… read more here.
Keywords: throughput drug; teratoid rhabdoid; atypical teratoid; drug screening ... See more keywords
Rhabdoid Tumors Are Immunogenic and May Respond to Immunotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2019-171
Abstract: Despite their low mutational burden (TMB), human rhabdoid tumors provoke an immune response. read more here.
Keywords: may respond; immunogenic may; tumors immunogenic; rhabdoid ... See more keywords
Switch/Sucrose Non-Fermentable Complex-Deficient Rhabdoid Carcinoma of Stomach: A Rare Case Report and Literature Review.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgical pathology"
DOI: 10.1177/10668969221146204
Abstract: Gastric undifferentiated/rhabdoid carcinoma is a rare highly invasive tumor of epithelial origin. Due to mutations in the switch/sucrose non-fermentable (SWI/SNF) complex, these tumor cells are usually dedifferentiated, presenting a characteristic rhabdoid profile. In this report,… read more here.
Keywords: switch sucrose; sucrose non; rhabdoid carcinoma; tumor ... See more keywords
ARID1A deficient undifferentiated spindle cell and rhabdoid sarcoma of the prostate: report of a unique case with emphasis on diagnostic implications
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostic Pathology"
DOI: 10.1186/s13000-022-01198-4
Abstract: Background SWItch Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex functions collectively as a tumor suppressor and the inactivation of any of its constituent components is frequently associated with tumor initiation and/or progression. Most SWI/SNF deficient tumors share… read more here.
Keywords: tumor; undifferentiated spindle; spindle cell; rhabdoid ... See more keywords
Germline BAP1 Mutation in a Family With Multi-Generational Meningioma With Rhabdoid Features: A Case Series and Literature Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.721712
Abstract: Meningioma is the most common primary brain tumor, and recurrence risk increases with increasing WHO Grade from I to III. Rhabdoid meningiomas are a subset of WHO Grade III tumors with rhabdoid cells, a high… read more here.
Keywords: bap1; meningioma rhabdoid; rhabdoid features; rhabdoid ... See more keywords
Molecular Heterogeneity in Pediatric Malignant Rhabdoid Tumors in Patients With Multi-Organ Involvement
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.932337
Abstract: Rhabdoid tumors (RTs) of the brain (atypical teratoid/rhabdoid tumor; AT/RT) and extracranial sites (most often the kidney; RTK) are malignant tumors predominantly occurring in children, frequently those with SMARCB1 germline alterations. Here we present data… read more here.
Keywords: organ involvement; patients multi; rhabdoid tumors; multi organ ... See more keywords