Co‐occurrence of schwannomatosis and rhabdoid tumor predisposition syndrome 1
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.412
Abstract: The clinical phenotype associated with germline SMARCB1 mutations has as yet not been fully documented. It is known that germline SMARCB1 mutations may cause rhabdoid tumor predisposition syndrome (RTPS1) or schwannomatosis. However, the co‐occurrence of… read more here.
Keywords: rhabdoid tumor; tumor predisposition; schwannomatosis; predisposition syndrome ... See more keywords
Atypical teratoid/rhabdoid tumor in adults: a systematic review of the literature with meta-analysis and additional reports of 4 cases
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DOI: 10.1007/s11060-022-03959-z
Abstract: Atypical teratoid/rhabdoid tumor (AT/RT) is a highly aggressive embryonal CNS neoplasm, characterized by inactivation of SMARCB1 (INI1) or rarely of SMARCA4 (BRG1). While it is predominantly a childhood tumor, AT/RT is rare in adults. We… read more here.
Keywords: tumor; review; atypical teratoid; teratoid rhabdoid ... See more keywords
Identification of Hub Genes in Atypical Teratoid/Rhabdoid Tumor by Bioinformatics Analyses
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DOI: 10.1007/s12031-020-01587-8
Abstract: Atypical teratoid/rhabdoid tumor (ATRT) is a devastating intracranial tumor in children. Currently, its molecular mechanisms cannot be studied effectively because patient samples are limited, and many factors are involved in its pathogenesis. In this study,… read more here.
Keywords: rhabdoid tumor; teratoid rhabdoid; atypical teratoid; hub genes ... See more keywords
Extrarenal rhabdoid tumor presented with an immobile arm in a one-year-old boy
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DOI: 10.1016/j.braindev.2017.04.001
Abstract: Infants with an immobile arm may be easily overlooked in primary care settings. Differential diagnoses include injuries, infections, neuropathies, ischemia and rarely, neoplasms. We report the case of a one-year-old boy with weakness in his… read more here.
Keywords: rhabdoid tumor; one year; immobile arm; year old ... See more keywords
Rhabdoid tumor of the liver: Report of 6 pediatric cases treated at a single institute.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2017.09.005
Abstract: BACKGROUND Rhabdoid tumors (RTs) of the liver are rare, aggressive and nonsecreting malignancies occurring mainly during the first year of life. Definition of RT relies on characteristic morphology and on the inactivation of the SMARCB1… read more here.
Keywords: rhabdoid tumor; nonsecreting hepatoblastomas; diagnosis; long term ... See more keywords
Synchronous Central Nervous System Atypical Teratoid/Rhabdoid Tumor and Malignant Rhabdoid Tumor of the Kidney: Case Report of a Long-Term Survivor and Review of the Literature.
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DOI: 10.1016/j.wneu.2017.11.158
Abstract: BACKGROUND Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system (CNS) with synchronous or metachronous extra-CNS disease is a rare childhood malignancy with a dismal prognosis. CASE DESCRIPTION We report a 7-week-old female with metastatic… read more here.
Keywords: rhabdoid tumor; cns; case; report ... See more keywords
Discovery of Dual Lysine Methyltransferase G9a and EZH2 Inhibitors with In Vivo Efficacy against Malignant Rhabdoid Tumor.
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DOI: 10.1021/acs.jmedchem.3c00003
Abstract: In recent years, it has been proposed that G9a/EZH2 dual inhibition is a promising cancer treatment strategy. Herein, we present the discovery of G9a/EZH2 dual inhibitors that merge the pharmacophores of G9a and EZH2 inhibitors.… read more here.
Keywords: g9a ezh2; tumor; rhabdoid tumor; ezh2 inhibitors ... See more keywords
Disseminated Congenital Malignant Rhabdoid Tumor Misdiagnosed as Multiple Congenital Hemangiomas.
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DOI: 10.1097/mph.0000000000001587
Abstract: To the Editor: A congenital malignant rhabdoid tumor (MRT) is a rare and aggressive growth, which is fatal in almost all patients under the age of 1 year.1 A 1-day-old girl, born at term by… read more here.
Keywords: malignant rhabdoid; congenital hemangiomas; multiple congenital; congenital malignant ... See more keywords
Diplopia Related to a Pediatric Cervical Rhabdoid Tumor in 18F-FDG PET.
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DOI: 10.1097/rlu.0000000000004327
Abstract: ABSTRACT Increased muscle uptake is commonly seen with 18F-FDG PET/CT because of an important physiological muscle glucose metabolism. Muscle uptake can express a recent significant muscle activity. However, the absence of muscle uptake is almost… read more here.
Keywords: 18f fdg; rhabdoid tumor; muscle; fdg pet ... See more keywords
FDG PET/CT Findings of Malignant Rhabdoid Tumor Arising From a Renal Allograft.
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DOI: 10.1097/rlu.0000000000004657
Abstract: ABSTRACT Malignant rhabdoid tumor of the kidney is a rare aggressive malignancy with poor prognosis. We describe FDG PET/CT findings in a case of malignant rhabdoid tumor of the renal allograft with regional lymph node… read more here.
Keywords: pet findings; malignant rhabdoid; rhabdoid tumor; fdg pet ... See more keywords
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine
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DOI: 10.1158/1078-0432.ccr-19-2717
Abstract: Purpose: Rhabdoid tumors are devastating pediatric cancers in need of improved therapies. We sought to identify small molecules that exhibit in vitro and in vivo efficacy against preclinical models of rhabdoid tumor. Experimental Design: We… read more here.
Keywords: rhabdoid tumor; tumor; rhabdoid tumors; hht ... See more keywords