Inhibition of PKC‐δ reduce rhabdomyolysis‐induced acute kidney injury
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17331
Abstract: Despite extensive research, the mechanisms underlying rhabdomyolysis‐induced acute kidney injury (AKI) remain largely elusive. In this study, we established both cell and murine models of rhabdomyolysis‐induced AKI by using myoglobin and glycerin, respectively, and provided… read more here.
Keywords: acute kidney; kidney injury; induced acute; rhabdomyolysis induced ... See more keywords
Myoglobin-driven ET-1 production and downstream activation of TRPC3- but not TRPC6-dependent vasoconstriction contributes to rhabdomyolysis-induced AKI
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732590
Abstract: Acute kidney injury (AKI) is the most severe and life-threatening complication of rhabdomyolysis, with 10-40% of patients developing some form of kidney insufficiency within days. Experimental evidence indicates that renal vasoconstriction plays a significant role… read more here.
Keywords: production; physiology; rhabdomyolysis induced; trpc3 trpc6 ... See more keywords
Rhabdomyolysis-induced renal ion accumulation promotes early acute kidney injury in sickle cell mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733429
Abstract: Individuals with sickle cell disease (SCD) are at greater risk for developing rhabdomyolysis, a potentially life-threatening syndrome resulting from the breakdown of skeletal muscle fibers. Acute kidney injury (AKI) is one of the most severe… read more here.
Keywords: rhabdomyolysis; kidney; physiology; rhabdomyolysis induced ... See more keywords
Rhabdomyolysis induced by rosuvastatin combined with entecavir: a case report
Sign Up to like & getrecommendations! Published in 2022 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-022-07254-0
Abstract: Background Rhabdomyolysis is a serious and potentially life threatening condition that can be caused by drugs. We report a case of acute hepatitis B with rhabdomyolysis after treatment with rosuvastatin and entecavir. Case presentation A… read more here.
Keywords: rhabdomyolysis; entecavir case; report; rosuvastatin ... See more keywords
Pharmacological Inhibition of Fatty Acid-Binding Protein 4 (FABP4) Protects Against Rhabdomyolysis-Induced Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00917
Abstract: Acute kidney injury (AKI) is a common and potentially life-threatening complication. Studies confirmed that circulating FABP4 depended on renal function of AKI patients. In our previous study, FABP4 was involved in the pathogenesis of I/R-induced… read more here.
Keywords: kidney injury; fabp4; inhibition; rhabdomyolysis ... See more keywords
Rhabdomyolysis-Induced AKI (RIAKI) Including the Role of COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158215
Abstract: Rhabdomyolysis is a compound disease that may be induced by many factors, both congenital and acquired. Statin therapy is considered one of the most common acquired factors. However, recent scientific reports suggest that serious complications… read more here.
Keywords: rhabdomyolysis; statin therapy; therapy; covid ... See more keywords
Pharmacological Inhibition of Macrophage Toll-like Receptor 4/Nuclear Factor-kappa B Alleviates Rhabdomyolysis-induced Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Medical Journal"
DOI: 10.4103/0366-6999.213406
Abstract: Background: Acute kidney injury (AKI) is the most common and life-threatening systemic complication of rhabdomyolysis. Inflammation plays an important role in the development of rhabdomyolysis-induced AKI. This study aimed to investigate the kidney model of… read more here.
Keywords: rhabdomyolysis; tlr4 kgr; macrophage; rhabdomyolysis induced ... See more keywords