Constitutively active Rheb mutants [T23M] and [E40K] drive increased production and secretion of recombinant protein in Chinese hamster ovary cells
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DOI: 10.1002/bit.27748
Abstract: Monoclonal antibodies (mAbs) are high value agents used for disease therapy (“biologic drugs”) or as diagnostic tools which are widely used in the healthcare sector. They are generally manufactured in mammalian cells, in particular Chinese… read more here.
Keywords: protein; constitutively active; rheb; chinese hamster ... See more keywords