LAUSR

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR.

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1 Published in 2020 at "Cell reports"

DOI: 10.1016/j.celrep.2020.107571

Abstract: Mechanistic target of rapamycin complex 1 (mTORC1) is a master modulator of cellular growth, and its aberrant regulation is recurrently documented within breast cancer. While the small GTPase Rheb1 is the canonical activator of mTORC1,… read more here.

Keywords: rheb1 independent; mutations mtor; mtorc1 activation; mtorc1 ... See more keywords