Chemogenetic inhibition of amygdala excitatory neurons impairs rhEPO-enhanced contextual fear memory after TBI
Sign Up to like & getrecommendations! Published in 2023 at "Neuroscience Letters"
DOI: 10.2139/ssrn.4385210
Abstract: Erythropoietin (EPO) is a hypoxia-responsive cytokine that induces neuroprotective effect in hypoxic-ischaemic, traumatic, excitotoxic and inflammatory injuries. Recently, utilizing a clinically relevant murine model of TBI and delayed hypoxemia, we have found that ongoing recombinant… read more here.
Keywords: excitatory neurons; tbi; fear memory; contextual fear ... See more keywords
Efficacy and Safety of Daprodustat Vs rhEPO for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis
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DOI: 10.3389/fphar.2022.746265
Abstract: Introduction: Daprodustat, a novel hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), its efficacy and safety remain unclear. Thus, we conducted this meta-analysis aiming at investigating its efficacy and safety on the treatment of patients with chronic kidney… read more here.
Keywords: safety; ckd patients; analysis; daprodustat ... See more keywords
Further Evidence of Neuroprotective Effects of Recombinant Human Erythropoietin and Growth Hormone in Hypoxic Brain Injury in Neonatal Mice
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DOI: 10.3390/ijms23158693
Abstract: Experimental in vivo data have recently shown complementary neuroprotective actions of rhEPO and growth hormone (rhGH) in a neonatal murine model of hypoxic brain injury. Here, we hypothesized that rhGH and rhEPO mediate stabilization of… read more here.
Keywords: brain; growth hormone; hypoxic brain; injury ... See more keywords