Preparation and Characterization of Site-Specific Fatty Chain-Modified Recombinant Human Granulocyte Colony Stimulating Factor
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DOI: 10.3389/fbioe.2022.923059
Abstract: The clinical use of recombinant human granulocyte colony-stimulating factor (rhG-CSF) is limited by its short serum half-life. In this study, a long-acting strategy for site-specific modification of rhG-CSF with 1-pentadecyl-1H-pyrrole-2,5-dione (C15 fatty chain-maleimide, C15-MAL) was… read more here.
Keywords: rhg; recombinant human; c15 rhg; rhg csf ... See more keywords
Stable reconstructed human gingiva–microbe interaction model: Differential response to commensals and pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.991128
Abstract: Background To investigate human oral health and disease, models are required which represent the interactions between the oral mucosa and microbiome. Our aim was to develop an organotypic model which maintains viability of both host… read more here.
Keywords: rhg; reconstructed human; human gingiva; model ... See more keywords