Articles with "rhgh" as a keyword



Overexpression, overproduction, purification, and characterization of rhGH in Escherichia coli

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Published in 2020 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.1902

Abstract: Overexpression of insoluble human growth hormone (hGH) in cytoplasm was achieved by E. coli Rosetta‐gami B(DE3) [pET21a (+)‐hGH]). For overexpression of hGH, effects of eight factors including temperature, type and concentration of carbon source, IPTG… read more here.

Keywords: overexpression; overexpression overproduction; rhgh; rhgh production ... See more keywords

Evaluation of fibronectin 1 in one dried blood spot and in urine after rhGH treatment.

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Published in 2017 at "Drug testing and analysis"

DOI: 10.1002/dta.2108

Abstract: Since the appearance of recombinant human growth hormone (rhGH) in the 1980s, its expansion and acquisition through the black market has increased, so the detection of its abuse continues to be a challenge. New biomarkers… read more here.

Keywords: one dried; spot urine; rhgh; blood spot ... See more keywords

Effect of long-acting PEGylated growth hormone for catch-up growth in children with idiopathic short stature: a 2-year real-world retrospective cohort study

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Published in 2024 at "European Journal of Pediatrics"

DOI: 10.1007/s00431-024-05719-9

Abstract: Several evidence gaps exist regarding the use of long-acting polyethylene glycol recombinant human growth hormone (PEG-rhGH) in children with idiopathic short stature (ISS), particularly studies conducted in real-world settings, with long-term follow-up, involving varied dosing… read more here.

Keywords: year; rhgh; daily rhgh; peg rhgh ... See more keywords

Real-Life Growth Hormone Treatment Patterns in Children from China: A Report from Two Databases

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Published in 2025 at "Advances in Therapy"

DOI: 10.1007/s12325-025-03204-9

Abstract: Although recombinant human growth hormone (rhGH) treatment has been established in China for many years for treating short stature (SS), there exists a lacuna on the current status and potential problems associated with effective usage… read more here.

Keywords: growth hormone; treatment; rhgh treatment; rhgh ... See more keywords

P182125 YEARS OF GROWTH HORMONE TREATMENT IN CHILDREN WITH CHRONIC KIDNEY DISEASE IN POLAND - RESULTS OF NATIONAL MULTICENTER STUDY

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Published in 2017 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p1821

Abstract: Growth retardation is one of considerable problems in children with chronic kidney disease (CKD) with a great impact on life activity and quality of life. Recombinant human growth hormone (rhGH) treatment has been used for… read more here.

Keywords: children ckd; rhgh; treatment; growth velocity ... See more keywords

Adult Height of Patients with SHOX Haploinsufficiency with or without GH Therapy: A Real-World Single-Center Study

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Published in 2022 at "Hormone Research in Paediatrics"

DOI: 10.1159/000524374

Abstract: Introduction: Isolated SHOX haploinsufficiency is a common monogenic cause of short stature. Few studies compare untreated and rhGH-treated patients up to adult height (AH). Our study highlights a growth pattern from childhood to AH in… read more here.

Keywords: rhgh; patients shox; rhgh treated; adult height ... See more keywords

Effect of Growth Hormone Therapy on Pubertal Timing: Systematic Review and Meta-analysis.

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Published in 2023 at "Hormone research in paediatrics"

DOI: 10.1159/000530578

Abstract: Introduction Recombinant human growth hormone (rhGH) therapy effectively increases height in various disorders of childhood growth. However, whether rhGH affects pubertal timing is unclear. We aimed to review systematically published evidence on the effect of… read more here.

Keywords: growth; rhgh; pubertal timing; growth hormone ... See more keywords

Response to rhGH therapy in short children born at very low birth weight.

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Published in 2024 at "Hormone research in paediatrics"

DOI: 10.1159/000542570

Abstract: INTRODUCTION Although the clinical benefits of long-term rhGH therapy have been well demonstrated in children born small for gestational age (SGA), little is known about the outcomes of this therapy in children born with very… read more here.

Keywords: rhgh therapy; rhgh; children born; response rhgh ... See more keywords

Approach to growth hormone therapy in children with chronic kidney disease varies across North America: the Midwest Pediatric Nephrology Consortium report

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Published in 2017 at "BMC Nephrology"

DOI: 10.1186/s12882-017-0599-1

Abstract: BackgroundGrowth impairment remains common in children with chronic kidney disease (CKD). Available literature indicates low level of recombinant human growth hormone (rhGH) utilization in short children with CKD. Despite efforts at consensus guidelines, lack of… read more here.

Keywords: nephrology; pediatric nephrology; rhgh; endocrinology ... See more keywords

Evaluating the effect of recombinant human growth hormone treatment on sleep-related breathing disorders in toddlers with Prader–Willi syndrome: a one-year retrospective cohort study

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Published in 2024 at "BMC Pediatrics"

DOI: 10.1186/s12887-023-04513-0

Abstract: Background Recombinant human growth hormone (rhGH) therapy is beneficial for children with Prader–Willi syndrome (PWS) in improving short stature and metabolism, but the effect of early rhGH treatment on respiratory and sleep parameters for PWS… read more here.

Keywords: treatment; rhgh; recombinant human; human growth ... See more keywords

The efficacy and safety of rhGH treatment combined with letrozole/GnRHa in adolescent boys

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Published in 2025 at "BMC Pediatrics"

DOI: 10.1186/s12887-025-05408-y

Abstract: In boys during puberty who were undergoing recombinant human growth hormone (rhGH) treatment, we compared the therapeutic efficacy on growth, and any adverse reactions, of co-therapy with either letrozole or gonadotropin-releasing hormone analog (GnRHa). Fifty-six… read more here.

Keywords: rhgh; group; gnrha; letrozole group ... See more keywords