Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12168
Abstract: Abstract Background Hypoxia is considered a key factor in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific mechanism driving polypogenesis under hypoxic conditions is unclear. This study aimed to explore hypoxia‐induced… read more here.
Keywords: ciliogenesis; nasal polyps; nasal epithelial; hypoxia ... See more keywords
Comparative short‐term efficacy of endoscopic sinus surgery and biological therapies in chronic rhinosinusitis with nasal polyps: A network meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12269
Abstract: Abstract Background To compare the safety and efficacy between endoscopic sinus surgery and different biologics in treating chronic rhinosinusitis with nasal polyps in adults by reviewing the existing clinical trials. Methods Data extraction and risk… read more here.
Keywords: sinus surgery; nasal polyps; endoscopic sinus; efficacy ... See more keywords
Biomarkers in the evaluation and management of chronic rhinosinusitis with nasal polyposis
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4547-2
Abstract: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a group of multifactorial and heterogeneous disorders with a significant economic strain on society, likely made up of different endotypes, each with a unique pathomechanism. In addition to… read more here.
Keywords: rhinosinusitis nasal; evaluation management; nasal polyposis; chronic rhinosinusitis ... See more keywords
The relationship between endoscopic and radiologic findings and olfactory status of patients with chronic rhinosinusitis with nasal polyps before and after the endoscopic sinus surgery
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5221-z
Abstract: IntroductionThis study was attempted to investigate the relationship between radiologic and endoscopic findings and pre- and post-operative olfactory scores in chronic rhinosinusitis with nasal polyps.Materials and methodsIn this study, 40 patients aged 19–64 years with chronic… read more here.
Keywords: rhinosinusitis nasal; olfactory status; surgery; chronic rhinosinusitis ... See more keywords
The postoperative outcomes of patients with chronic rhinosinusitis with nasal polyps by sustained released steroid from hyaluronic acid gel
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-020-06320-0
Abstract: The self-crosslinked hyaluronic acid (scHA) and steroids are considered as efficient factors for postoperative management after chronic rhinosinusitis (CRS) nasal surgery. This randomized clinical trial is designed to investigate the efficacy and potential of scHA… read more here.
Keywords: rhinosinusitis nasal; chronic rhinosinusitis; scha; patients chronic ... See more keywords
Budesonide transnasal pulsating nebulization after surgery in chronic rhinosinusitis with nasal polyps.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-00979-6
Abstract: Intranasal corticosteroid drugs are widely used in chronic rhinosinusitis with nasal polyps (CRSwNP). In contrast to classical delivery with nasal pump sprays, pulsating aerosols can deliver significant doses into superior and posterior sinonasal spaces. A… read more here.
Keywords: rhinosinusitis nasal; pulsating nebulization; nasal polyps; chronic rhinosinusitis ... See more keywords
Endoplasmic reticulum stress exacerbates inflammation in chronic rhinosinusitis with nasal polyps via the transcription factor XBP1.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical immunology"
DOI: 10.1016/j.clim.2020.108659
Abstract: Endoplasmic reticulum (ER) stress results in the activation of the unfolded protein response (UPR), a process that is involved in the pathogenesis of many inflammatory diseases. However, the role of ER stress in chronic rhinosinusitis… read more here.
Keywords: rhinosinusitis nasal; endoplasmic reticulum; chronic rhinosinusitis; inflammation ... See more keywords
Usefulness of endonasal mucoplasty in the surgical treatment of chronic rhinosinusitis with nasal polyps. Prospective study.
Sign Up to like & getrecommendations! Published in 2021 at "Acta otorrinolaringologica espanola"
DOI: 10.1016/j.otoeng.2020.08.003
Abstract: Chronic Rhinosinusitis with Nasal Polyps (CRScPN) is a disease with great impact on health. The surgical option using endoscopic nasosinus surgery is the therapeutic alternative when control of the disease is not achieved with medical… read more here.
Keywords: rhinosinusitis nasal; treatment; chronic rhinosinusitis; study ... See more keywords
Obstructive sleep apnea in patients with chronic rhinosinusitis with nasal polyps: a cross-sectional study.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2019.06.006
Abstract: INTRODUCTION Adults with chronic rhinosinusitis with nasal polyps (CRSwNP) often suffer from sleep disruption and sleep apnea. As the apneic profile of CRSwNP may differ from obstructive sleep apnea (OSA) classic patients without nasal polyps… read more here.
Keywords: nasal polyps; apnea; sleep apnea; study ... See more keywords
Relative frequencies of symptoms and risk factors among patients with chronic rhinosinusitis with nasal polyps using a case-control study
Sign Up to like & getrecommendations! Published in 2018 at "Acta Oto-Laryngologica"
DOI: 10.1080/00016489.2017.1366052
Abstract: Abstract Objectives: The aim of this study was to investigate the relative frequency of important symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP), the link between CRSwNP and the lower airways and the importance of… read more here.
Keywords: rhinosinusitis nasal; among patients; nasal polyps; chronic rhinosinusitis ... See more keywords
Otitis media in severe asthma associated with chronic rhinosinusitis with nasal polyps: a new therapeutic target for biologics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asthma"
DOI: 10.1080/02770903.2022.2033262
Abstract: Abstract Background: Chronic rhinosinusitis with nasal polyps (CRSwNPs) is associated with otitis media with effusion (OME) in about 25% of cases. The objective of this study was to assess the clinical efficacy of the 4… read more here.
Keywords: nasal polyps; asthma; otitis media; chronic rhinosinusitis ... See more keywords