Articles with "rhlf glycan" as a keyword



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Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities

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Published in 2020 at "Investigational New Drugs"

DOI: 10.1007/s10637-020-01020-2

Abstract: Lactoferrin has gained extensive attention due to its ample biological properties. In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce… read more here.

Keywords: recombinant human; apoptosis; lactoferrin; cytotoxicity ... See more keywords