Clinical-grade intranasal NGF fuels neurological and metabolic functions of Mecp2-deficient mice
Sign Up to like & getrecommendations! Published in 2024 at "Brain"
DOI: 10.1093/brain/awae291
Abstract: Abstract MECP2 deficiency causes a broad spectrum of neuropsychiatric disorders that can affect both genders. Rett syndrome is the most common and is characterized by an apparently normal growth period followed by a regression phase… read more here.
Keywords: mice; grade; rhngf; mecp2 null ... See more keywords
Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.822359
Abstract: Nerve growth factor (NGF) is the best characterized neurotrophin, and it is known to play an important role in ocular homeostasis. Here, we demonstrated the expression of NGF receptors in adult zebrafish retina and optimized… read more here.
Keywords: degeneration; administration rhngf; zebrafish model; intravitreal administration ... See more keywords