Designing Single-Component Optogenetic Membrane Recruitment Systems: The Rho-Family GTPase Signaling Toolbox.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00604
Abstract: We describe the efficient creation of single-component optogenetic tools for membrane recruitment-based signaling perturbation using BcLOV4 technology. The workflow requires two plasmids to create six different domain arrangements of the dynamic membrane binder BcLOV4, a… read more here.
Keywords: gtpase; family gtpase; single component; rho family ... See more keywords
The neglected terminators: Rho family GAPs in neutrophils
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DOI: 10.1111/eci.12993
Abstract: GTPase‐activating proteins (GAPs) accelerate the rate of hydrolysis of GTP bound to small GTPases, thereby limiting the prevalence and concentration of the active, GTP‐bound form of these proteins. The large number of potential GAPs acting… read more here.
Keywords: gaps neutrophils; rho family; family; neglected terminators ... See more keywords