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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.

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0 Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109102

Abstract: Megakaryocytes (MKs), the precursors of blood platelets, are large, polyploid cells residing mainly in the bone marrow. We have previously shown that balanced signaling of the Rho GTPases RhoA and Cdc42 is critical for correct… read more here.

Keywords: cdc42 signaling; cytoplasmic maturation; cdc42; rhoa cdc42 ... See more keywords