LncRNA CTC-497E21.4 promotes the progression of gastric cancer via modulating miR-22/NET1 axis through RhoA signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Gastric Cancer"
DOI: 10.1007/s10120-019-00998-w
Abstract: Background Long non-coding RNAs (lncRNAs) have emerged as important roles in gastric cancer (GC). However, the role of the dysregulated lncRNAs in GC remained large unknown. We investigated the clinical significance, biological function and mechanism… read more here.
Keywords: ctc 497e21; gastric cancer; signaling pathway; ctc ... See more keywords
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0025-5
Abstract: Atypical brain connectivity is a major contributor to the pathophysiology of neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 is one of several genes in the 16p11.2 microdeletion region, but whether it contributes to… read more here.
Keywords: taok2; activity causes; taok2 activity; autism ... See more keywords
N6-methyladenosine reader YTHDF1 promotes ARHGEF2 translation and RhoA signaling in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Gastroenterology"
DOI: 10.1053/j.gastro.2021.12.269
Abstract: BACKGROUND & AIMS N6-methyladenosine (m6A) governs the fate of RNAs through m6A readers. Colorectal cancer (CRC) exhibits aberrant m6A modifications and expression of m6A regulators. However, how m6A readers interpret oncogenic m6A methylome to promote… read more here.
Keywords: rhoa signaling; m6a; ythdf1; ythdf1 promotes ... See more keywords
Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.258767
Abstract: Epithelia migrate as physically coherent populations of cells. Earlier studies revealed that mechanical stress accumulates in these cellular layers as they move. These stresses are characteristically tensile in nature and have often been inferred to… read more here.
Keywords: signaling stabilizes; enhanced rhoa; cell; cadherin ... See more keywords
Relationship between NogoA/NgR1/RhoA signaling pathway and the apoptosis of cerebral neurons after cerebral infarction in rats.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202203_28316
Abstract: The article "Relationship between NogoA/NgR1/RhoA signaling pathway and the apoptosis of cerebral neurons after cerebral infarction in rats, by Y.-X. Xie, M. Zhang, C.-R. Zhang, F. Chen, published in Eur Rev Med Pharmacol Sci 2020;… read more here.
Keywords: apoptosis; relationship nogoa; nogoa ngr1; signaling pathway ... See more keywords