Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling
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DOI: 10.3389/fimmu.2022.980539
Abstract: Strategies based on intracellular expression of artificial binding domains present several advantages over manipulating nucleic acid expression or the use of small molecule inhibitors. Intracellularly-functional nanobodies can be considered as promising macrodrugs to study key… read more here.
Keywords: gtpase rhoa; tripartite split; split gfp; rhoa subfamily ... See more keywords