Synthesis of 2‐Substituted 2‐Amino Ketones by Rhodium‐Catalyzed Reaction of N‐Sulfonyl‐1,2,3‐triazoles with 2‐Alkenols
Sign Up to like & getrecommendations! Published in 2017 at "Helvetica Chimica Acta"
DOI: 10.1002/hlca.201600320
Abstract: A study on a rhodium(II)-catalyzed reaction of N-sulfonyl-1,2,3-triazoles with 2-alkenols is reported. The reaction is initiated by insertion of an α-imino carbene into the O–H linkage of alcohol, forming a 2-alkenoxy enamide intermediate. A thermal… read more here.
Keywords: triazoles alkenols; reaction sulfonyl; rhodium catalyzed; sulfonyl triazoles ... See more keywords
Synthesis of xanthones from 4-(2-phenoxyphenyl)-1-tosyl-1H-1,2,3-triazole via rhodium-catalyzed annulation/oxidation
Sign Up to like & getrecommendations! Published in 2021 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2021.106360
Abstract: Abstract A series of xanthone derivatives were synthesized by rhodium-catalyzed cycloaddition and sequential oxidation. The derivatives synthesized for excellent yields, including electron-withdrawing and electron-donating substituents, demonstrated the wide applicability of the proposed approach. The xanthones… read more here.
Keywords: oxidation; synthesis xanthones; xanthones phenoxyphenyl; rhodium catalyzed ... See more keywords
Rhodium-catalyzed directed C–H functionalization of 2-arylindazoles with diazotized Meldrum's acid
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2021.122009
Abstract: Abstract A rhodium-catalyzed alcohol-mediated ortho-functionalization of 2-aryl-2H-indazoles through sequential C-H activation and carbenoid insertion with diazotized Meldrum's acid was developed. Using the 2H-indazole as the directing group and alcohol as the alkyl source, a series… read more here.
Keywords: catalyzed directed; rhodium catalyzed; diazotized meldrum; functionalization ... See more keywords
Rhodium-catalyzed synthesis of 2,3 – Disubstituted N-methoxy pyrroles and furans via [3+2] cycloaddition between metal carbenoids and activated olefins
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.04.007
Abstract: Abstract For the first time, we report the synthesis of 2-substituted N -alkoxy pyrrole 3-carboxylate and furan 3-carboxylate via Rh-catalyzed [3+2] cycloaddition between α-diazo oxime ether or α -diazo carbonyl compounds with vinyl equivalents in… read more here.
Keywords: cycloaddition; rhodium catalyzed; disubstituted methoxy; synthesis disubstituted ... See more keywords
Rhodium-Catalyzed (5 + 2) and (5 + 1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks.
Sign Up to like & getrecommendations! Published in 2019 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.9b00477
Abstract: Cycloaddition reactions are a hallmark in organic synthesis because they provide an efficient way to construct highly substituted carbo- and heterocycles found in natural products and pharmaceutical agents. Most cycloadditions occur under thermal or photochemical… read more here.
Keywords: cycloaddition; carbon; rhodium catalyzed; five carbon ... See more keywords
Enantioselective Rhodium-Catalyzed Allylation of Aliphatic Imines: Synthesis of Chiral C-Aliphatic Homoallylic Amines.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02069
Abstract: Reported herein is a method for the efficient syntheses of optically active 1-alkyl homoallylic amines in yields up to 95%, 13.5:1 dr, and 98% ee under mild, aqueous reaction conditions, via the Rh-catalyzed asymmetric allylation… read more here.
Keywords: catalyzed allylation; enantioselective rhodium; homoallylic amines; rhodium catalyzed ... See more keywords
Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02133
Abstract: A rhodium-catalyzed carbonylative transformation of unactivated phenols to aryl salicylates is described. This protocol is characterized by utilizing 1,3-rhodium migration as the key step to provide direct access to synthesize o-hydroxyaryl esters. Various desired aryl… read more here.
Keywords: unactivated phenols; rhodium catalyzed; carbonylative synthesis; aryl salicylates ... See more keywords
Rhodium-Catalyzed Denitrogenative Diazole-Triazole Coupling toward Aza-Bridged Structures and Imidazole-Based Chelating Ligands.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01092
Abstract: 1,4,8-Triazaocta-1,3,5,7-tetraenes, generated in situ by Rh2(Piv)4-catalyzed denitrogenative coupling of pyrazoles with 1-sulfonyl-1,2,3-triazoles, smoothly form 2,6,8-triazabicyclo[3.2.1]octa-3,6-dienes via intramolecular aza-Diels-Alder cycloaddition. This domino reaction, combined with the subsequent thermal or acid-catalyzed rearrangement of the cycloadducts, provides direct… read more here.
Keywords: catalyzed denitrogenative; rhodium catalyzed; diazole triazole; triazole coupling ... See more keywords
Asymmetric Synthesis of 3-Methyleneindolines via Rhodium(I)-Catalyzed Alkynylative Cyclization of N-(o-Alkynylaryl)imines.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01518
Abstract: The first asymmetric synthesis of 3-methyleneindolines from alkynyl imines has been developed via a rhodium-catalyzed tandem process: regioselective alkynylation of the internal alkynes and subsequent intramolecular addition to the imines. The reaction proceeded with unconventional… read more here.
Keywords: via rhodium; rhodium catalyzed; synthesis methyleneindolines; asymmetric synthesis ... See more keywords
Rhodium-Catalyzed β-Dehydroborylation of Silyl Enol Ethers: Access to Highly Functionalized Enolates.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03796
Abstract: An efficient rhodium-catalyzed β-dehydroborylation of aldehyde-derived silyl enol ethers (SEEs) with bis(pinacolato)diboron (B2pin2) is disclosed. The borylation reactions proceeded well with alkyl- and aryl-substituted SEEs, affording a wide array of valuable functionalized β-boryl silyl enolates… read more here.
Keywords: silyl enol; catalyzed dehydroborylation; enol ethers; rhodium catalyzed ... See more keywords
Rhodium-Catalyzed Atroposelective C-H/C-H Cross-Coupling Reaction between 1-Aryl Isoquinoline Derivatives and Indolizines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04002
Abstract: A rhodium-catalyzed asymmetric oxidative C-H/C-H cross-coupling reaction between 1-aryl isoquinolines and indolizines is disclosed. With a matched pair of SCpRh complex and chiral carboxylic acid, enantioselective two-fold C-H/C-H cross-coupling reactions between 1-aryl isoquinolines and indolizines… read more here.
Keywords: cross coupling; coupling reaction; reaction aryl; cross ... See more keywords