Detection of Raspberry Ketone after Percutaneous Absorption of Rhododendrol-Containing Cosmetics and Its Mechanism of Formation
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DOI: 10.3390/cosmetics8040097
Abstract: Here, we aimed to elucidate the mechanism of rhododendrol (RD)-induced leukoderma. We investigated the skin permeability of RD in an aqueous solution and in different cosmetic formulations (lotion and emulsion) in an in vitro skin… read more here.
Keywords: absorption; mechanism; mechanism formation; rhododendrol ... See more keywords
Biochemical Mechanism of Rhododendrol-Induced Leukoderma
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DOI: 10.3390/ijms19020552
Abstract: RS-4-(4-hydroxyphenyl)-2-butanol (rhododendrol (RD))—a skin-whitening ingredient—was reported to induce leukoderma in some consumers. We have examined the biochemical basis of the RD-induced leukoderma by elucidating the metabolic fate of RD in the course of tyrosinase-catalyzed oxidation.… read more here.
Keywords: induced leukoderma; rhododendrol; tyrosinase; biochemical mechanism ... See more keywords