Rhodomyrtus tomentosa Leaf Extract and Rhodomyrtone Combat Streptococcus pneumoniae Biofilm and Inhibit Invasiveness to Human Lung Epithelial and Enhance Pneumococcal Phagocytosis by Macrophage
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DOI: 10.1007/s00284-020-02164-3
Abstract: Rhodomyrtus tomentosa leaf has been traditionally used to treat many infections. This plant species has been documented to possess a wide spectrum of pharmacological effects. This study aimed to determine the effects of Rhodomyrtus tomentosa… read more here.
Keywords: extract rhodomyrtone; rhodomyrtus tomentosa; tomentosa leaf; leaf extract ... See more keywords
Immunomodulatory effects of Rhodomyrtus tomentosa leaf extract and its derivative compound, rhodomyrtone, on head kidney macrophages of rainbow trout (Oncorhynchus mykiss)
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DOI: 10.1007/s10695-017-0452-2
Abstract: Rhodomyrtus tomentosa is a medicinal plant that shows biological effects including immunomodulatory activity on human and other mammals but not in fish. In this study, we evaluated the in vitro immunomodulatory effects of R. tomentosa… read more here.
Keywords: rhodomyrtus tomentosa; tomentosa leaf; leaf extract; rhodomyrtone ... See more keywords
Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles.
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DOI: 10.1016/j.micpath.2018.12.019
Abstract: Sigma factor B (SigB) controls the expression of Staphylococcus aureus genes including virulence factors and plays a role in the bacterial secretion system through membrane vesicle production. Inhibition of SigB could attenuate SigB dependent virulence… read more here.
Keywords: membrane vesicles; rhodomyrtone; sigb; sigb activity ... See more keywords
Rhodomyrtone Accumulates in Bacterial Cell Wall and Cell Membrane and Inhibits the Synthesis of Multiple Cellular Macromolecules in Epidemic Methicillin-Resistant Staphylococcus aureus
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DOI: 10.3390/antibiotics10050543
Abstract: As the burden of antibacterial resistance worsens and treatment options become narrower, rhodomyrtone—a novel natural antibiotic agent with a new antibacterial mechanism—could replace existing antibiotics for the treatment of infections caused by multi-drug resistant Gram-positive… read more here.
Keywords: rhodomyrtone; epidemic methicillin; methicillin resistant; cell wall ... See more keywords