Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.
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DOI: 10.1016/j.bbrc.2017.08.078
Abstract: Rhodospirillum rubruml-asparaginase mutant RrA E149R, V150P, F151T (RrA) was previously identified to down-regulate telomerase activity along with catalyzing the hydrolysis of l-asparagine. The aim of this study was to define the effect of prolonged RrA… read more here.
Keywords: rra; telomerase; telomerase activity; inhibition ... See more keywords