Rhoptry neck protein 11 has crucial roles during malaria parasite sporozoite invasion of salivary glands and hepatocytes.
Sign Up to like & getrecommendations! Published in 2019 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2019.05.001
Abstract: The malaria parasite sporozoite sequentially invades mosquito salivary glands and mammalian hepatocytes; and is the Plasmodium lifecycle infective form mediating parasite transmission by the mosquito vector. The identification of several sporozoite-specific secretory proteins involved in… read more here.
Keywords: malaria parasite; invasion; neck protein; parasite sporozoite ... See more keywords
Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding study
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183198
Abstract: Malaria, a disease endemic in many tropical and subtropical regions, is caused by infection of the erythrocyte by the apicomplexan parasite Plasmodium. Host-cell invasion is a complex process but two Plasmodium proteins, Apical Membrane Antigen… read more here.
Keywords: protein; apical membrane; vivax; reactivity ... See more keywords
PLASMOpred: A Machine Learning-Based Web Application for Predicting Antimalarial Small Molecules Targeting the Apical Membrane Antigen 1–Rhoptry Neck Protein 2 Invasion Complex
Sign Up to like & getrecommendations! Published in 2025 at "Pharmaceuticals"
DOI: 10.3390/ph18060776
Abstract: Objective: Falciparum malaria is a major global health concern, affecting more than half of the world’s population and causing over half a million deaths annually. Red cell invasion is a crucial step in the parasite’s… read more here.
Keywords: apical membrane; neck protein; rhoptry neck; machine ... See more keywords