Evidence of depression-associated circadian rhythm disruption and regret in prostate cancer patients after surgery
Sign Up to like & getrecommendations! Published in 2017 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-017-3913-3
Abstract: PurposeThe purpose of this study is to investigate the association between prostate cancer (PCa) patients’ regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood,… read more here.
Keywords: rhythm disruption; depression; surgery; circadian rhythm ... See more keywords
Circadian rhythm disruption in critically ill patients
Sign Up to like & getrecommendations! Published in 2023 at "Acta Physiologica"
DOI: 10.1111/apha.13962
Abstract: Patients admitted to the intensive care unit (ICU) are in need of continuous organ replacement strategies and specialized care, for example because of neurological dysfunction, cardio‐pulmonary instability, liver or kidney failure, trauma, hemorrhagic or septic… read more here.
Keywords: ill patients; critically ill; disruption critically; rhythm disruption ... See more keywords
Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12803
Abstract: Circadian rhythm disruption (CRD) represents a major contributor to tumor proliferation. Nonetheless, the role of CRD in the clinical prediction of cancer outcomes has not been well studied. In this study, we developed a computational… read more here.
Keywords: cell; analysis; single cell; rhythm disruption ... See more keywords
RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pineal research"
DOI: 10.1111/jpi.12885
Abstract: Hypoxia-ischemia (HI) of the brain not only impairs neurodevelopment but also causes pineal gland dysfunction, which leads to circadian rhythm disruption. However, the underlying mechanism of circadian rhythm disruption associated with HI-induced pineal dysfunction remains… read more here.
Keywords: pineal dysfunction; rhythm disruption; circadian rhythm;
Circadian Rhythm Disruption and Alzheimer’s Disease: The Dynamics of a Vicious Cycle
Sign Up to like & getrecommendations! Published in 2020 at "Current Neuropharmacology"
DOI: 10.2174/1570159x18666200429013041
Abstract: All mammalian cells exhibit circadian rhythm in cellular metabolism and energetics. Autonomous cellular clocks are modulated by various pathways that are essential for robust time keeping. In addition to the canonical transcriptional translational feedback loop,… read more here.
Keywords: rhythm disruption; clock; rhythm; physiology ... See more keywords