A green stability-indicating RP-HPLC-UV method using factorial design for determination of ribavirin, sofosbuvir and ledipasvir: Application to average content, acid degradation kinetics and in vitro drug interactions study
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DOI: 10.1016/j.microc.2020.105251
Abstract: Abstract A novel optimization approach based on full factorial design was generated for developing a green, rapid and simple RP- HPLC-UV gradient method for simultaneous assay of recent antiviral drugs of hepatitis C (sofosbuvir and… read more here.
Keywords: sofosbuvir ledipasvir; ribavirin sofosbuvir; method;