IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology Research"
DOI: 10.1111/hepr.12715
Abstract: Older patients with chronic hepatitis C have a lower virological response to interferon (IFN)‐based treatments compared to younger patients. A single nucleotide polymorphism in the IFN‐λ‐4 (IFNL4) gene has a potent predictive effect on treatment… read more here.
Keywords: ifn; ribavirin therapy; therapy older; chronic hepatitis ... See more keywords
Long-term surveillance of liver histological changes in chronic hepatitis C patients completing pegylated interferon-α plus ribavirin therapy: an observational cohort study
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DOI: 10.1177/20406223211067631
Abstract: Background: For chronic hepatitis C (CHC) patients completing pegylated interferon (PegIFN)-α/ribavirin therapy, long-term liver histological changes remain largely unexplored. Methods: This observational cohort study included 85 CHC patients completing PegIFN-α/ribavirin therapy with liver biopsies performed… read more here.
Keywords: svr cases; patients completing; liver histological; ribavirin therapy ... See more keywords
Hepatitis B Surface Antigen Decline During Sofosbuvir and Ribavirin Therapy in Hepatitis B Inactive Carriers Who were co-infected with Hepatitis C.
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DOI: 10.2169/internalmedicine.7337-21
Abstract: Direct-acting antiviral (DAA) therapy carries a potential risk of inducing hepatitis B virus (HBV) reactivation. However, the HBV kinetics during and after DAA therapy in patients co-infected with hepatitis C virus (HCV) and HBV remain… read more here.
Keywords: hepatitis; sofosbuvir ribavirin; inactive carriers; infected hepatitis ... See more keywords