Articles with "ribbon synapses" as a keyword



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Repeated Moderate Sound Exposure Causes Accumulated Trauma to Cochlear Ribbon Synapses in Mice

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Published in 2020 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2019.12.049

Abstract: Repeated induction of a temporary threshold shift (TTS) may result in a permanent threshold shift (PTS) and is thought to be associated with early onset of age-related hearing loss (ARHL). The possibility that a PTS… read more here.

Keywords: repeated moderate; ribbon synapses; noise; sound exposure ... See more keywords
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Hidden hearing loss is associated with loss of ribbon synapses of cochlea inner hair cells

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Published in 2021 at "Bioscience Reports"

DOI: 10.1042/bsr20201637

Abstract: Abstract The present study aimed to observe the changes in the cochlea ribbon synapses after repeated exposure to moderate-to-high intensity noise. Guinea pigs received 95 dB SPL white noise exposure 4 h a day for… read more here.

Keywords: ribbon synapses; loss; mtmi noise; noise ... See more keywords
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Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses

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Published in 2022 at "eLife"

DOI: 10.1101/2022.05.10.491334

Abstract: Ribbon synapses of cochlear inner hair cells (IHCs) are specialized to indefatigably transmit sound information at high rates. To understand the underlying mechanisms, structure-function analysis of the active zone (AZ) of these synapses is essential.… read more here.

Keywords: ribbon synapses; ribbon; structure function; electron tomography ... See more keywords
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Macrophages Are Dispensable for Postnatal Pruning of the Cochlear Ribbon Synapses

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Published in 2021 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2021.736120

Abstract: Ribbon synapses of cochlear hair cells undergo pruning and maturation before the hearing onset. In the central nervous system (CNS), synaptic pruning was mediated by microglia, the brain-resident macrophages, via activation of the complement system.… read more here.

Keywords: macrophages dispensable; ribbon synapses; postnatal pruning; pruning cochlear ... See more keywords
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Lead exposure induces nitrative stress and disrupts ribbon synapses in the cochlea

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Published in 2022 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.934630

Abstract: Environmental exposure to heavy metal lead, a public health hazard in many post-industrial cities, causes hearing impairment upon long-term exposure. Lead-induced cochlear and vestibular dysfunction is well-documented in animal models. Although short-term exposure to lead… read more here.

Keywords: ribbon synapses; nitrative stress; lead exposure; exposure ... See more keywords
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Ribbon Synapses and Retinal Disease: Review

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24065090

Abstract: Synaptic ribbons are presynaptic protein complexes that are believed to be important for the transmission of sensory information in the visual system. Ribbons are selectively associated with those synapses where graded changes in membrane potential… read more here.

Keywords: synapses retinal; ribbon synapses; ribbon; retinal disease ... See more keywords