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Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.12.049
Abstract: Repeated induction of a temporary threshold shift (TTS) may result in a permanent threshold shift (PTS) and is thought to be associated with early onset of age-related hearing loss (ARHL). The possibility that a PTS…
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Keywords:
repeated moderate;
ribbon synapses;
noise;
sound exposure ... See more keywords
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Published in 2021 at "Bioscience Reports"
DOI: 10.1042/bsr20201637
Abstract: Abstract The present study aimed to observe the changes in the cochlea ribbon synapses after repeated exposure to moderate-to-high intensity noise. Guinea pigs received 95 dB SPL white noise exposure 4 h a day for…
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Keywords:
ribbon synapses;
loss;
mtmi noise;
noise ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.1101/2022.05.10.491334
Abstract: Ribbon synapses of cochlear inner hair cells (IHCs) are specialized to indefatigably transmit sound information at high rates. To understand the underlying mechanisms, structure-function analysis of the active zone (AZ) of these synapses is essential.…
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Keywords:
ribbon synapses;
ribbon;
structure function;
electron tomography ... See more keywords
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Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.736120
Abstract: Ribbon synapses of cochlear hair cells undergo pruning and maturation before the hearing onset. In the central nervous system (CNS), synaptic pruning was mediated by microglia, the brain-resident macrophages, via activation of the complement system.…
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Keywords:
macrophages dispensable;
ribbon synapses;
postnatal pruning;
pruning cochlear ... See more keywords
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Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.934630
Abstract: Environmental exposure to heavy metal lead, a public health hazard in many post-industrial cities, causes hearing impairment upon long-term exposure. Lead-induced cochlear and vestibular dysfunction is well-documented in animal models. Although short-term exposure to lead…
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Keywords:
ribbon synapses;
nitrative stress;
lead exposure;
exposure ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065090
Abstract: Synaptic ribbons are presynaptic protein complexes that are believed to be important for the transmission of sensory information in the visual system. Ribbons are selectively associated with those synapses where graded changes in membrane potential…
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Keywords:
synapses retinal;
ribbon synapses;
ribbon;
retinal disease ... See more keywords