DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC).
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DOI: 10.1021/jacs.2c07217
Abstract: Ribonuclease targeting chimeras (RiboTACs) induce degradation of an RNA target by facilitating an interaction between an RNA and a ribonuclease (RNase). We describe the screening of a DNA-encoded library (DEL) to identify binders of monomeric… read more here.
Keywords: ribonuclease targeting; ribonuclease; encoded library; ribotac ... See more keywords