A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
Sign Up to like & getrecommendations! Published in 2019 at "Nature nanotechnology"
DOI: 10.1038/s41565-019-0539-2
Abstract: Delivery technologies for the CRISPR-Cas9 (CRISPR, clustered regularly interspaced short palindromic repeats) gene editing system often require viral vectors, which pose safety concerns for therapeutic genome editing1. Alternatively, cationic liposomal components or polymers can be… read more here.
Keywords: gene editing; ribonucleoprotein complex; genome; nanocapsule ... See more keywords
The β-1,3-Glucanase Degrades Callose at Plasmodesmata to Facilitate the Transport of the Ribonucleoprotein Complex in Pyrus betulaefolia
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098051
Abstract: Grafting is widely used to improve the stress tolerance and the fruit yield of horticultural crops. Ribonucleoprotein complexes formed by mRNAs and proteins play critical roles in the communication between scions and stocks of grafted… read more here.
Keywords: transport ribonucleoprotein; pyrus betulaefolia; glucanase; ribonucleoprotein ... See more keywords
Components and Architecture of the Rhabdovirus Ribonucleoprotein Complex
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12090959
Abstract: Rhabdoviruses, as single-stranded, negative-sense RNA viruses within the order Mononegavirales, are characterised by bullet-shaped or bacteroid particles that contain a helical ribonucleoprotein complex (RNP). Here, we review the components of the RNP and its higher-order… read more here.
Keywords: ribonucleoprotein complex; rhabdovirus ribonucleoprotein; components architecture; ribonucleoprotein ... See more keywords