Calcium‐Mobilizing Behaviors of Neutral Cyclic ADP‐Ribose Mimics that Integrate Modifications to the Nucleobase, Northern Ribose and Pyrophosphate
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DOI: 10.1002/cbic.201800133
Abstract: Cyclic adenosine diphosphate ribose (cADPR) is an endogenous Ca2+ mobilizer involved in diverse cellular processes. Mimics of cADPR play a crucial role in investigating the molecular mechanism(s) of cADPR‐mediated signaling. Here, compound 3, a mimic… read more here.
Keywords: behaviors neutral; pyrophosphate; calcium mobilizing; northern ribose ... See more keywords
CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses
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DOI: 10.1038/s41467-022-28549-5
Abstract: Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O -methylated at the 2‘ position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here we show that the… read more here.
Keywords: cap adjacent; required reward; localization; reward learning ... See more keywords
Exogenous D-ribose promotes gentamicin treatment of several drug-resistant Salmonella
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DOI: 10.3389/fmicb.2022.1053330
Abstract: The metabolic microenvironment of bacteria impacts drug efficacy. However, the metabolic mechanisms of drug-resistant Salmonella spp. remain largely unknown. This study characterized the metabolic mechanism of gentamicin-resistant Salmonella Choleraesuis and found that D-ribose increased the… read more here.
Keywords: metabolism; ribose; salmonella; resistant salmonella ... See more keywords