Synthetic Activity of Recombinant Whole Cell Biocatalysts Containing 2‐Deoxy‐D‐ribose‐5‐phosphate Aldolase from Pectobacterium atrosepticum
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200147
Abstract: In nature 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA) catalyses the reversible formation of 2‐deoxyribose 5‐phosphate from D‐glyceraldehyde 3‐phosphate and acetaldehyde. In addition, this enzyme can use acetaldehyde as the sole substrate, resulting in a tandem aldol reaction, yielding… read more here.
Keywords: cell; phosphate aldolase; pectobacterium atrosepticum; whole cell ... See more keywords
Rational design to enhance the catalytic activity of 2-deoxy-D-ribose-5-phosphate aldolase from Pseudomonas syringae pv. syringae B728a.
Sign Up to like & getrecommendations! Published in 2021 at "Protein expression and purification"
DOI: 10.1016/j.pep.2021.105863
Abstract: The 2-Deoxy-D-ribose-5-phosphate aldolase (DERA) enzyme in psychrophilic bacteria has gradually attracted the attention of researchers. A novel gene, deoC (681 bp), encoding DERAPsy, was identified in Pseudomonas syringae pv. syringae B728a, recombinantly expressed in E.… read more here.
Keywords: deoxy ribose; syringae; phosphate aldolase; ribose phosphate ... See more keywords
An industrially applied biocatalyst: 2-Deoxy-d-ribose-5- phosphate aldolase
Sign Up to like & getrecommendations! Published in 2017 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2017.08.001
Abstract: Abstract 2-Deoxy- d -ribose-5-phosphate aldolase (DERA) belongs to the family of lyases and can form C–C bonds to generate multiple chiral centers, thus providing an interesting route to produce key chiral compounds. However, several problems,… read more here.
Keywords: deoxy ribose; ribose phosphate; dera; phosphate aldolase ... See more keywords
A biocatalytically active membrane obtained from immobilization of 2-deoxy-D-ribose-5-phosphate aldolase on a porous support.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b12029
Abstract: Aldol reactions play an important role in organic synthesis, as they belong to the class of highly beneficial C-C-linking reactions. Aldol type reactions can be efficiently and stereoselectively catalyzed by the enzyme 2-Deoxy-D-ribose-5-phosphate aldolase (DERA)… read more here.
Keywords: deoxy ribose; immobilization; phosphate aldolase; ribose phosphate ... See more keywords
Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001468
Abstract: The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken–egg dilemma, which describes that enzymes are… read more here.
Keywords: iron; reaction; metabolic network; ribose phosphate ... See more keywords
Reduced Ribose-5-Phosphate Isomerase A-1 Expression in Specific Neurons and Time Points Promotes Longevity in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12010124
Abstract: Deregulation of redox homeostasis is often associated with an accelerated aging process. Ribose-5-phosphate isomerase A (RPIA) mediates redox homeostasis in the pentose phosphate pathway (PPP). Our previous study demonstrated that Rpi knockdown boosts the healthspan… read more here.
Keywords: phosphate; caenorhabditis elegans; rpia knockdown; rpia ... See more keywords