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   Articles with "ribosomal biogenesis" as a keyword



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Genetic mutations in ribosomal biogenesis gene TCOF1 identified in human neural tube defects

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recommendations! Published in 2023 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.2150

Abstract: Rare mutations in multiple genes have been associated with human neural tube defects (NTDs), but their causative roles in NTDs disease are poorly understood. Insufficiency of the ribosomal biogenesis gene treacle ribosome biogenesis factor 1(Tcof1)… read more here.

Keywords: human neural; biogenesis; tube defects; tcof1 ... See more keywords
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Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc

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recommendations! Published in 2022 at "Haematologica"

DOI: 10.1101/2022.02.03.478956

Abstract: The homeobox transcription factors HoxA9 and Meis1 are causally involved in the etiology of acute myeloid leukemia. While HoxA9 immortalizes cells, cooperation with Meis1 is necessary to induce malignancy. Here, we apply degron techniques to… read more here.

Keywords: myc; stimulation; hoxa9; ribosomal biogenesis ... See more keywords
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Ribosomal biogenesis as an emerging target of neurodevelopmental pathologies

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recommendations! Published in 2019 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14576

Abstract: Development of the nervous system is carried out by complex gene expression programs that are regulated at both transcriptional and translational level. In addition, quality control mechanisms such as the TP53‐mediated apoptosis or neuronal activity‐stimulated… read more here.

Keywords: ribosomal biogenesis; biogenesis emerging; neurodevelopmental pathologies; emerging target ... See more keywords
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Puf3 participates in ribosomal biogenesis in malaria parasites

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recommendations! Published in 2018 at "Journal of Cell Science"

DOI: 10.1242/jcs.212597

Abstract: ABSTRACT In this study, we characterized the Puf family gene member Puf3 in the malaria parasites Plasmodium falciparum and Plasmodium yoelii. Secondary structure prediction suggested that the RNA-binding domains of the Puf3 proteins consisted of… read more here.

Keywords: ribosomal biogenesis; pfpuf3; malaria parasites; puf3 ... See more keywords
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The glycolytic enzyme ALDOA and the exon junction complex protein RBM8A are regulators of ribosomal biogenesis

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recommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.954358

Abstract: Cellular growth is a fundamental process of life and must be precisely controlled in multicellular organisms. Growth is crucially controlled by the number of functional ribosomes available in cells. The production of new ribosomes depends… read more here.

Keywords: rbm8a; exon junction; growth; ribosomal biogenesis ... See more keywords

TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus: Implications for p53 Regulation and Neurite Outgrowth

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22052280

Abstract: Transient receptor potential vanilloids (TRPV1) are non-selective cation channels that sense and transduce inflammatory pain signals. We previously reported that activation of TRPV1 induced the translocation of β-arrestin2 (ARRB2) from the cytoplasm to the nucleus,… read more here.

Keywords: neurite outgrowth; arrb2; ribosomal biogenesis; activation ... See more keywords