Inhibition of translation termination by small molecules targeting ribosomal release factors
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DOI: 10.1038/s41598-019-51977-1
Abstract: The bacterial ribosome is an important drug target for antibiotics that can inhibit different stages of protein synthesis. Among the various classes of compounds that impair translation there are, however, no known small-molecule inhibitors that… read more here.
Keywords: ribosomal release; small molecules; translation; termination ... See more keywords