Ribosomal Synthesis of Thioether-Bridged Bicyclic Peptides.
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DOI: 10.1007/978-1-4939-6451-2_5
Abstract: Many biologically active peptides found in nature exhibit a bicyclic structure wherein a head-to-tail cyclic backbone is further constrained by an intramolecular linkage connecting two side chains of the peptide. Accordingly, methods to access macrocyclic… read more here.
Keywords: bridged bicyclic; ribosomal synthesis; thioether bridged; synthesis thioether ... See more keywords