Atomic modeling of the ITS2 ribosome assembly subcomplex from cryo‐EM together with mass spectrometry‐identified protein–protein crosslinks
Sign Up to like & getrecommendations! Published in 2017 at "Protein Science"
DOI: 10.1002/pro.3045
Abstract: The assembly of ribosomal subunits starts in the nucleus, initiated by co‐transcriptional folding of nascent ribosomal RNA (rRNA) transcripts and binding of ribosomal proteins and assembly factors. The internal transcribed spacer 2 (ITS2) is a… read more here.
Keywords: mass spectrometry; ribosome assembly; modeling its2; assembly ... See more keywords
Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in parasitology"
DOI: 10.1016/j.pt.2016.12.003
Abstract: In Liu et al., the authors present a 2.5-Å structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise assembly of the large-subunit ribosomal RNA (rRNA). Based on this study,… read more here.
Keywords: ribosome assembly; assembly trypanosomatids; trypanosomatids novel; ribosome ... See more keywords
Ribosome assembly coming into focus
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-018-0078-y
Abstract: In the past 25 years, genetic and biochemical analyses of ribosome assembly in yeast have identified most of the factors that participate in this complex pathway and have generated models for the mechanisms driving the… read more here.
Keywords: coming focus; assembly coming; ribosome assembly; microscopy ... See more keywords
Role of ribosome assembly in Escherichia coli ribosomal RNA degradation
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky808
Abstract: Abstract DEAD-Box proteins (DBPs) constitute a prominent class of RNA remodeling factors that play a role in virtually all aspects of RNA metabolism. To better define their cellular functions, deletions in the genes encoding each… read more here.
Keywords: degradation; ribosomal rna; escherichia coli; ribosome assembly ... See more keywords
A DEAD-box protein regulates ribosome assembly through control of ribosomal protein synthesis
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz502
Abstract: Abstract DEAD-box proteins (DBPs) comprise a large family of proteins that most commonly have been identified as regulators of ribosome assembly. The Escherichia coli DBP, SrmB, represents a model bacterial DBP whose absence impairs formation… read more here.
Keywords: protein; protein synthesis; ribosome assembly; dead box ... See more keywords
Era, a GTPase-like protein of the Ras family, does not control ribosome assembly in Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001200
Abstract: Era GTPase is universally present in microbes including Mycobacterium tuberculosis (Mtb) complex bacteria. While Era is known to regulate ribosomal assembly in Escherichia coli and predicted to be essential for in vitro growth, its function… read more here.
Keywords: mycobacterium tuberculosis; ribosome assembly; era gtpase; gtpase ... See more keywords
Attachment of the RNA degradosome to the bacterial inner cytoplasmic membrane prevents wasteful degradation of rRNA in ribosome assembly intermediates
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3001942
Abstract: RNA processing and degradation shape the transcriptome by generating stable molecules that are necessary for translation (rRNA and tRNA) and by facilitating the turnover of mRNA, which is necessary for the posttranscriptional control of gene… read more here.
Keywords: ribosome assembly; rna degradosomes; rna; rna degradosome ... See more keywords
When a ribosomal protein grows up - the ribosome assembly path of Rps3
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Cell"
DOI: 10.15698/mic2017.05.571
Abstract: The biogenesis of ribosomes is a central process in all dividing cells. Eukaryotic ribosomes are composed of a large 60S and a small 40S subunit, each comprising a complex assembly of ribosomal RNA (rRNA) and… read more here.
Keywords: protein; rrna; assembly path; ribosome assembly ... See more keywords
Eukaryotic Ribosome Biogenesis: The 40S Subunit
Sign Up to like & getrecommendations! Published in 2022 at "Acta Naturae"
DOI: 10.32607/actanaturae.11540
Abstract: The formation of eukaryotic ribosomes is a sequential process of ribosomal precursors maturation in the nucleolus, nucleoplasm, and cytoplasm. Hundreds of ribosomal biogenesis factors ensure the accurate processing and formation of the ribosomal RNAs’ tertiary… read more here.
Keywords: ribosome assembly; eukaryotic ribosome; 40s subunit; ribosome biogenesis ... See more keywords
Regulatory Connections Between the Cyanobacterial Factor PipX and the Ribosome Assembly GTPase EngA
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.781760
Abstract: Cyanobacteria, phototrophic organisms performing oxygenic photosynthesis, must adapt their metabolic processes to important environmental challenges, like those imposed by the succession of days and nights. Not surprisingly, certain regulatory proteins are found exclusively in this… read more here.
Keywords: nitrogen; ribosome assembly; assembly gtpase; gtpase enga ... See more keywords
A Mutant Era GTPase Suppresses Phenotypes Caused by Loss of Highly Conserved YbeY Protein in Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.896075
Abstract: Ribosome assembly is a complex fundamental cellular process that involves assembling multiple ribosomal proteins and several ribosomal RNA species in a highly coordinated yet flexible and resilient manner. The highly conserved YbeY protein is a… read more here.
Keywords: ribosome assembly; highly conserved; 16s rrna; era ... See more keywords