Genome-wide Survey of Ribosome Collision.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107610
Abstract: Ribosome movement is not always smooth and is rather often impeded. For ribosome pauses, fundamental issues remain to be addressed, including where ribosomes pause on mRNAs, what kind of RNA/amino acid sequence causes this pause,… read more here.
Keywords: collided ribosomes; ribosome collision; wide survey; genome wide ... See more keywords
Ribosome Collision Is Critical for Quality Control during No-Go Decay.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.08.019
Abstract: No-go decay (NGD) is a eukaryotic quality control mechanism that evolved to cope with translational arrests. The process is characterized by an endonucleolytic cleavage near the stall sequence, but the mechanistic details are unclear. Our… read more here.
Keywords: quality control; quality; ribosome collision; cleavage ... See more keywords
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cell"
DOI: 10.1016/j.molcel.2022.02.031
Abstract: Innate immune responses induce hundreds of interferon-stimulated genes (ISGs). Viperin, a member of the radical S-adenosyl methionine (SAM) superfamily of enzymes, is the product of one such ISG that restricts the replication of a broad… read more here.
Keywords: viperin triggers; viperin; ribosome collision; translation inhibition ... See more keywords