Ribosome-dependent conformational flexibility changes and RNA dynamics of IRES domains revealed by differential SHAPE
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DOI: 10.1038/s41598-018-23845-x
Abstract: Internal ribosome entry site (IRES) elements are RNA regions that recruit the translation machinery internally. Here we investigated the conformational changes and RNA dynamics of a picornavirus IRES upon incubation with distinct ribosomal fractions. Differential… read more here.
Keywords: rna dynamics; differential shape; ribosome dependent; flexibility ... See more keywords