The ABC(E1)s of Ribosome Recycling and Reinitiation.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.05.017
Abstract: In a recent issue of Nature Structural & Molecular Biology, Heuer et al. (2017) present a 3.9-Å cryo-EM structure of the 40S:ABCE1 post-splitting complex. This structure provides new insights into a dual role for ABCE1 in… read more here.
Keywords: reinitiation; recycling reinitiation; abc ribosome; ribosome recycling ... See more keywords
Mechanisms of ribosome recycling in bacteria and mitochondria: a structural perspective
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2067712
Abstract: ABSTRACT In all living cells, the ribosome translates the genetic information carried by messenger RNAs (mRNAs) into proteins. The process of ribosome recycling, a key step during protein synthesis that ensures ribosomal subunits remain available… read more here.
Keywords: mitochondria structural; bacteria mitochondria; mechanisms ribosome; ribosome recycling ... See more keywords
The kinetic mechanism of bacterial ribosome recycling
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx694
Abstract: Abstract Bacterial ribosome recycling requires breakdown of the post-termination complex (PoTC), comprising a messenger RNA (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon bound to the 70S ribosome. The translation… read more here.
Keywords: trna release; mrna trna; ribosome recycling; bacterial ribosome ... See more keywords
Ribosome recycling in mRNA translation, quality control, and homeostasis
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DOI: 10.1515/hsz-2019-0279
Abstract: Abstract Protein biosynthesis is a conserved process, essential for life. Ongoing research for four decades has revealed the structural basis and mechanistic details of most protein biosynthesis steps. Numerous pathways and their regulation have recently… read more here.
Keywords: homeostasis; quality control; translation; ribosome recycling ... See more keywords
Ribosome recycling is coordinated by processive events in two asymmetric ATP sites of ABCE1
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DOI: 10.26508/lsa.201800095
Abstract: The stepwise ribosome disassembly in the translation cycle of eukaryotes and archaea is scheduled by discrete molecular events within the asymmetric ribosome recycling factor ABCE1. Ribosome recycling orchestrated by ABCE1 is a fundamental process in… read more here.
Keywords: abce1 ribosome; coordinated processive; processive events; ribosome recycling ... See more keywords
Ribosome recycling is not critical for translational coupling in Escherichia coli
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.59974
Abstract: We used ribosome profiling to characterize the biological role of ribosome recycling factor (RRF) in Escherichia coli. As expected, RRF depletion leads to enrichment of post-termination 70S complexes in 3′-UTRs. We also observe that elongating… read more here.
Keywords: translational coupling; ribosome recycling; escherichia coli;