Analyzing Ribosome Remodeling in Health and Disease
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DOI: 10.1002/pmic.202000039
Abstract: Increasing evidence suggests that ribosomes actively regulate protein synthesis. However, much of this evidence is indirect, leaving this layer of gene regulation largely unexplored, in part due to methodological limitations. Indeed, evidence is reviewed demonstrating… read more here.
Keywords: analyzing ribosome; ribosome remodeling; evidence; health disease ... See more keywords
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
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DOI: 10.1016/j.celrep.2019.11.025
Abstract: Summary Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding many ribosomal proteins (RPs) in axons, far away from neuronal cell bodies. Here, we report… read more here.
Keywords: locally synthesized; ribosomal proteins; ribosome remodeling; translation ... See more keywords