Ligand design for riboswitches, an emerging target class for novel antibiotics.
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DOI: 10.4155/fmc-2017-0063
Abstract: Riboswitches are cis-acting gene regulatory elements and constitute potential targets for new antibiotics. Recent studies in this field have started to explore these targets for drug discovery. New ligands found by fragment screening, design of… read more here.
Keywords: ligand design; design riboswitches; design; emerging target ... See more keywords