Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins
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DOI: 10.3390/toxins11100593
Abstract: Immunotoxins are chimeric molecules that combine the specificity of an antibody to recognize and bind tumor antigens with the potency of the enzymatic activity of a toxin, thus, promoting the death of target cells. Among… read more here.
Keywords: ribotoxin sarcin; furin cleavage; inclusion furin; cleavage site ... See more keywords