The proline‐rich domain of fission yeast WASp (Wsp1p) interacts with actin filaments and inhibits actin polymerization
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14571
Abstract: Members of the Wiskott–Aldrich Syndrome protein (WASp) family activate Arp2/3 complex (actin‐related proteins 2 and 3 complex) to form actin filament branches. The proline‐rich domain (PRD) of WASp contributes to branching nucleation, and the PRD… read more here.
Keywords: actin filaments; rich domain; proline rich; actin ... See more keywords
On the O-rich domain of the U-Am-O phase diagram
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nuclear Materials"
DOI: 10.1016/j.jnucmat.2020.151986
Abstract: Abstract Uranium–Americium oxides U1−yAmyO2±x are promising candidates as possible transmutation targets for next generation nuclear reactors. In the context of a comprehensive investigation of their thermodynamic and thermal properties, the behaviour in oxidizing conditions is… read more here.
Keywords: phase; domain phase; rich domain; domain ... See more keywords
Cholesterol-rich domain formation mediated by ZO proteins is essential for tight junction formation.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217561120
Abstract: Tight junctions (TJs) are cell-adhesion structures responsible for the epithelial barrier. We reported that accumulation of cholesterol at the apical junctions is required for TJ formation [K. Shigetomi, Y. Ono, T. Inai, J. Ikenouchi, J.… read more here.
Keywords: apical junctions; cholesterol rich; rich domain; formation cholesterol ... See more keywords
Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain
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DOI: 10.1126/sciadv.aau4202
Abstract: We report the first subnanometer resolution structure of the RET extracellular domain in complex with a ligand and co-receptor. Signaling through the receptor tyrosine kinase RET is essential during normal development. Both gain- and loss-of-function… read more here.
Keywords: structure; rich domain; cysteine rich; ret signaling ... See more keywords
The cation-π interaction in cysteine-rich domain of Smoothened is critical for its cholesterylation and function
Sign Up to like & getrecommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022090
Abstract: The Hedgehog (Hh) signaling pathway is critical for embryonic development and tissue renewal. The G protein-coupled receptor (GPCR)-like protein Smoothened (SMO) is the central signal transducer in the Hh pathway. Cholesterol binds and then covalently… read more here.
Keywords: cysteine rich; rich domain; cholesterylation; cation interaction ... See more keywords