Ricolinostat suppresses proliferation, promotes apoptosis, and enhances the antiproliferative activity of topoisomerase inhibitors in cervical cancer cells
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DOI: 10.1002/ddr.21999
Abstract: Ricolinostat has been found to exhibit anticancer effects alone and in combination with various chemotherapeutic drugs in several cancer types. However, to the best of our knowledge, the efficacy of ricolinostat in cervical cancer is… read more here.
Keywords: cervical cancer; cancer; proliferation; topoisomerase inhibitors ... See more keywords
Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma
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DOI: 10.1158/1078-0432.ccr-16-2526
Abstract: Purpose: Histone deacetylase (HDAC) inhibition improves the efficacy of proteasome inhibition for multiple myeloma but adds substantial toxicity. Preclinical models suggest that the observed synergy is due to the role of HDAC6 in mediating resistance… read more here.
Keywords: combination; bortezomib dexamethasone; ricolinostat; multiple myeloma ... See more keywords