Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases
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DOI: 10.1038/s41467-020-16729-0
Abstract: Biocatalysts that perform C–H hydroxylation exhibit exceptional substrate specificity and site-selectivity, often through the use of high valent oxidants to activate these inert bonds. Rieske oxygenases are examples of enzymes with the ability to perform… read more here.
Keywords: two rieske; rieske oxygenases; divergent; hydroxylation ... See more keywords
Design principles for site-selective hydroxylation by a Rieske oxygenase
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DOI: 10.1038/s41467-021-27822-3
Abstract: Rieske oxygenases exploit the reactivity of iron to perform chemically challenging C–H bond functionalization reactions. Thus far, only a handful of Rieske oxygenases have been structurally characterized and remarkably little information exists regarding how these… read more here.
Keywords: rieske; sxtt gxta; selectivity; site ... See more keywords