Autophagy markers are dysregulated in the endometrial tissues of patients with unexplained repeated implantation failure
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23654
Abstract: Endometrium decidualization is a complex biological process, which includes the interplay of transcription factors, cytokines, cell cycle regulators, and other signaling pathways. However, the underlying molecular mechanisms of this process are not fully elucidated to… read more here.
Keywords: endometrial tissues; autophagy markers; rif; implantation failure ... See more keywords
Recurrent implantation failure might be overestimated without PGT-A
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05775-0
Abstract: I read with interest the article by Bar et al. [1], which indicates that endometrial scratching should be considered as an additional tool for patients with recurrent implantation failure (RIF). It appears especially effective in… read more here.
Keywords: endometrial scratching; embryo; implantation; rif ... See more keywords
Effects of rifampicin on antineoplastic drug pyrotinib maleate pharmacokinetics in healthy subjects
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DOI: 10.1007/s10637-022-01241-7
Abstract: Pyrotinib (PTN), an irreversible EGFR/HER2 dual tyrosine kinase inhibitor used for treating HER2-positive breast cancer, is primarily metabolized by cytochrome P450 (CYP)3A4 isozyme. Rifampicin (RIF) is a strong index CYP3A4 inducer. Therefore, the study aimed… read more here.
Keywords: pyrotinib; study; rif; rifampicin antineoplastic ... See more keywords
Genetic polymorphisms of the cobalamin transport system are associated with idiopathic recurrent implantation failure
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-019-01455-4
Abstract: PurposeVitamin B12 (cobalamin, Cbl) plays a role in the recycling of folate, which is important in pregnancy. Transcobalamin II (TCN2) and transcobalamin receptor (TCblR) proteins are involved in the cellular uptake of Cbl. TCN2 binds… read more here.
Keywords: rif risk; tcn2 tcblr; rif; implantation failure ... See more keywords
Anti-tuberculosis site-specific oral delivery system that enhances rifampicin bioavailability in a fixed-dose combination with isoniazid.
Sign Up to like & getrecommendations! Published in 2020 at "Drug delivery and translational research"
DOI: 10.1007/s13346-020-00847-9
Abstract: The in vivo release segregation of rifampicin (RIF) and isoniazid (INH) has been proposed as a strategy to avoid RIF acid degradation, which is known as one of the main factors for reduced RIF bioavailability… read more here.
Keywords: inh; bioavailability; delivery; tuberculosis ... See more keywords
Very fast dissolving acid carboxymethylcellulose‐rifampicin matrix: Development and solid‐state characterization
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2016.10.013
Abstract: &NA; One of the main obstacles to the successful treatment of tuberculosis is the poor and variable oral bioavailability of rifampicin (RIF), which is mainly due to its low hydrophilicity and dissolution rate. The aim… read more here.
Keywords: solid state; rif; cmc rif; microscopy ... See more keywords
Isoniazid and rifampicin concentrations in children with tuberculosis with either a daily or intermittent regimen: implications for the revised RNTCP 2012 doses in India.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2017.12.004
Abstract: Suboptimal plasma drug concentrations in antitubercular therapy (ATT) may lead to delayed treatment response and the emergence of acquired drug resistance. This study aimed (i) to determine and compare plasma concentrations of isoniazid (INH) and… read more here.
Keywords: daily intermittent; intermittent; either daily; revised rntcp ... See more keywords
Evaluation of linezolid or trimethoprim/sulfamethoxazole in combination with rifampicin as alternative oral treatments based on an in vitro pharmacodynamic model of staphylococcal biofilm.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2018.01.014
Abstract: Combinations of linezolid (LZD) or trimethoprim/sulfamethoxazole (SXT) plus rifampicin (RIF) are alternative oral treatments for staphylococcal prosthetic joint infections (PJIs) when fluoroquinolones are not possible to use, but there is limited evidence regarding their activity.… read more here.
Keywords: combination; sxt; trimethoprim sulfamethoxazole; biofilm ... See more keywords
Pharmacokinetics of dolutegravir 100 mg once daily with rifampicin.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2019.04.009
Abstract: BACKGROUND Tuberculosis (TB) causes 25% of all deaths among individuals infected with human immunodeficiency virus (HIV). Rifampicin (RIF) is a potent inducer of drug metabolizing enzymes and drug transporters, and co-administration with dolutegravir (DTG) reduces… read more here.
Keywords: rifampicin; 100 daily; dtg 100; c24h ... See more keywords
Alwana oil: The traditional Amazigh olive oil of the Pre Rif (Northern Morocco)
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Gastronomy and Food Science"
DOI: 10.1016/j.ijgfs.2018.07.004
Abstract: Abstract Purpose of the research Alwana oil is a unconventional type of olive oil that has been prepared for centuries from roasted olives by women of Berber origin in the central Rif mountain. This study… read more here.
Keywords: alwana oil; oil traditional; rif; oil ... See more keywords
NQO1 and CYP450 reductase decrease the systemic exposure of rifampicin‐quinone and mediate its redox cycle in rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.09.040
Abstract: Graphical abstract Figure. No Caption available. HighlightsAn LC–MS method for the simultaneous determination of RIF and RIF‐Q was first developed and validated.A large amount of RIF‐Q was reduced to RIF and underwent redox cycle.CPR and… read more here.
Keywords: rif; redox cycle; systemic exposure;