A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx307
Abstract: Objectives To compare the efficacy of ceftazidime/avibactam plus tedizolid-based combination regimens with the standard therapy of azithromycin, ethambutol and rifabutin for the treatment of pulmonary Mycobacterium avium complex (MAC) disease. Methods We mimicked the human… read more here.
Keywords: ceftazidime avibactam; rifabutin; tedizolid moxifloxacin; mac ... See more keywords
Coadministration of Voriconazole and Rifabutin Can Increase the Risk of Adverse Drug Reactions in Patients With Multiple Infections
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DOI: 10.1097/ftd.0000000000001241
Abstract: Supplemental Digital Content is Available in the Text. Background: Coinfection of tuberculosis or nontuberculous mycobacteria and Aspergillus presents a challenge in medication selection because of the pharmacokinetic interactions between rifampin and voriconazole. Some researchers have… read more here.
Keywords: adverse drug; rifabutin; drug reactions; drug ... See more keywords
Intraocular deposits and cataracts after long-term rifabutin intake
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000020049
Abstract: Abstract Rationale: Rifabutin is a broad-spectrum antibiotic known to cause deposits on the corneal endothelium and lens. We report a patient in whom cataracts developed and progressive pigment deposits were seen on the corneal endothelium,… read more here.
Keywords: intraocular deposits; rifabutin intake; term rifabutin; long term ... See more keywords
Efficacy of Rifabutin‐Based Helicobacter pylori Eradication Regimen in Korea With High Prevalence of Tuberculosis Infection
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DOI: 10.1111/hel.70011
Abstract: As the antibiotic resistance and treatment failure rates of Helicobacter pylori are rising, the need for rescue therapy with rifabutin for H. pylori eradication (HPE) is also increasing. Therefore, in this study, we investigated the… read more here.
Keywords: pylori eradication; rifabutin; rifabutin based; efficacy ... See more keywords
Drug‐level change and optimal dose adjustment of tacrolimus with the use of rifabutin for treating mycobacterial disease in solid organ transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13893
Abstract: Little is known about the change in drug level and the need for dose adjustment of calcineurin inhibitor when it is used with rifabutin in solid organ transplant (SOT) recipients. We aimed to analyze whether… read more here.
Keywords: rifabutin; tacrolimus; adjustment; drug ... See more keywords
Population pharmacokinetics of rifabutin among HIV/TB co-infected children on lopinavir/ritonavir-based antiretroviral therapy
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DOI: 10.1128/aac.00354-24
Abstract: ABSTRACT In adults requiring protease inhibitor (PI)-based antiretroviral therapy (ART), replacing rifampicin with rifabutin is a preferred option, but there is lack of evidence to guide rifabutin dosing in children, especially with PIs. We aimed… read more here.
Keywords: antiretroviral therapy; rifabutin; based antiretroviral; pharmacokinetics rifabutin ... See more keywords
Rifabutin Is Bactericidal against Intracellular and Extracellular Forms of Mycobacterium abscessus
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DOI: 10.1128/aac.00363-20
Abstract: Mycobacterium abscessus is increasingly recognized as an emerging opportunistic pathogen causing severe lung diseases. As it is intrinsically resistant to most conventional antibiotics, there is an unmet medical need for effective treatments. Repurposing of clinically… read more here.
Keywords: rfb; mycobacterium abscessus; abscessus; intracellular extracellular ... See more keywords
Differential Impact of the rpoB Mutant on Rifampin and Rifabutin Resistance Signatures of Mycobacterium tuberculosis Is Revealed Using a Whole-Genome Sequencing Assay
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DOI: 10.1128/spectrum.00754-22
Abstract: Current approaches to diagnose drug-resistant MTB are time-consuming, consequently leading to inefficient intervention or further disease transmission. In this study, we curated lists of coding variants associated with differential rifampin and rifabutin resistant signatures using… read more here.
Keywords: time; rifampin rifabutin; rifabutin; mtb ... See more keywords
Comparison of Compartmental and Non-Compartmental Analysis to Detect Biopharmaceutical Similarity of Intravenous Nanomaterial-Based Rifabutin Formulations
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DOI: 10.3390/pharmaceutics15041258
Abstract: Pharmacometric analysis is often used to quantify the differences and similarities between formulation prototypes. In the regulatory framework, it plays a significant role in the evaluation of bioequivalence. While non-compartmental analysis provides an unbiased data… read more here.
Keywords: albumin stabilized; rifabutin; nanomaterial based; analysis ... See more keywords
Rifabutin as salvage therapy for Helicobacter pylori eradication: Cornerstones and novelties
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DOI: 10.3748/wjg.v28.i45.6356
Abstract: When several Helicobacter pylori eradication treatments fail, guidelines recommend a cultured guided approach; however, culture is not widely available. Therefore, a rifabutin based regimen could be the best solution. Rifabutin indeed shows a low rate… read more here.
Keywords: pylori eradication; therapy; rifabutin; eradication ... See more keywords
Superior Efficacy of Bismuth-Containing Rifabutin Quadruple Therapy over Rifabutin Triple Therapy as Salvage Treatment.
Sign Up to like & getrecommendations! Published in 2025 at "Gut and liver"
DOI: 10.5009/gnl250211
Abstract: Background/Aims Helicobacter pylori is a pathogen that causes chronic gastritis and peptic ulcer diseases and is a carcinogen responsible for the development of malignancies, including gastric cancer. In the current era of high antimicrobial resistance,… read more here.
Keywords: rifabutin; triple therapy; therapy; bismuth containing ... See more keywords