Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine
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DOI: 10.1002/cpt.1072
Abstract: Rifampin demonstrated dose‐dependent relative induction between cytochrome P (CYP)3A and P‐glycoprotein (P‐gp), organic anion transporting polypeptides (OATPs), or CYP2C9; P‐gp, OATP, and CYP2C9 induction was one drug–drug interaction (DDI) category lower than that observed for… read more here.
Keywords: rifabutin carbamazepine; carbamazepine; exposure; drug ... See more keywords