Inhalation of Respirable Crystalline Rifapentine Particles Induces Pulmonary Inflammation.
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DOI: 10.1021/acs.molpharmaceut.6b00905
Abstract: Rifapentine is an anti-tuberculosis (anti-TB) drug with a prolonged half-life, but oral delivery results in low concentrations in the lungs because of its high binding (98%) to plasma proteins. We have shown that inhalation of… read more here.
Keywords: delivery; rifapentine; rifapentine particles; inhalation ... See more keywords