Rifaximin has no effect on hemodynamics in decompensated cirrhosis: A randomized, double‐blind, placebo‐controlled trial
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28898
Abstract: Decompensated cirrhosis is characterized by disturbed systemic and splanchnic hemodynamics. Bacterial translocation from the gut is considered the key driver in this process. Intestinal decontamination with rifaximin may improve hemodynamics. This double‐blind, randomized, controlled trial… read more here.
Keywords: placebo; cirrhosis; effect; hemodynamics ... See more keywords
Repeat Rifaximin for Irritable Bowel Syndrome: No Clinically Significant Changes in Stool Microbial Antibiotic Sensitivity
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-017-4598-7
Abstract: BackgroundRifaximin has demonstrated efficacy and safety for diarrhea-predominant irritable bowel syndrome (IBS-D).AimTo determine the rifaximin repeat treatment effect on fecal bacterial antibiotic susceptibility.MethodsPatients with IBS in Trial 3 (TARGET 3) study who responded to open-label… read more here.
Keywords: irritable bowel; stool microbial; repeat; bowel syndrome ... See more keywords
Development and Validation of a Discriminatory Dissolution Method for Rifaximin Products.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2019.01.020
Abstract: The commercial product of rifaximin (RFX) contains α form. The α form can change to β form on exposure to high humidity that can occur during manufacturing, stability, and in-use period. It is critical to… read more here.
Keywords: dissolution method; method; form; discriminatory dissolution ... See more keywords
Characterization of Abdominal Pain Response in Patients with Diarrhea-Predominant Irritable Bowel Syndrome Treated with Rifaximin
Sign Up to like & getrecommendations! Published in 2017 at "Gastroenterology"
DOI: 10.1016/s0016-5085(17)33123-2
Abstract: Purpose: IBS is characterized by recurring abdominal pain associated with defecation or changes in bowel habits. IBS is further subcategorized based on the predominant bowel habit (eg, diarrhea-predominant IBS [IBS-D]). Abdominal pain is a key… read more here.
Keywords: ibs; response; abdominal pain; pain score ... See more keywords
Status of Rifaximin: A Review of Characteristics, Uses and Analytical Methods
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DOI: 10.1080/10408347.2018.1447355
Abstract: ABSTRACT Rifaximin, an oral antimicrobial, has many advantages because it is selective intestine, has minimal adverse effects and is used for the treatment of some diseases such as hepatic encephalopathy, irritable bowel syndrome, travelers' diarrhea,… read more here.
Keywords: rifaximin review; analytical methods; chemistry; status rifaximin ... See more keywords
Eco-Friendly Pharmaceutical Analysis of Rifaximin in Tablets by HPLC-MS and Microbiological Turbidimetry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmab044
Abstract: Rifaximin, an antimicrobial used for the treatment of various diseases, lacks analytical methods in official compendia for evaluation of the final product. This paper presents an eco-friendly protocol for rifaximin tablets by high performance liquid… read more here.
Keywords: eco friendly; rifaximin tablets; friendly pharmaceutical; method ... See more keywords
MINIATURIZED MICROBIOLOGICAL METHOD TO DETERMINE THE POTENCY OF RIFAXIMIN IN TABLETS.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsab017
Abstract: BACKGROUND Rifaximin, a semi-synthetic antimicrobial, does not present microbiological method described in official compendia, and in the literature there is a lack for this topic. The quality control of antimicrobials is extremely important to evaluate… read more here.
Keywords: potency rifaximin; rifaximin tablets; method; microbiological method ... See more keywords
Real‐world effects of long‐term rifaximin treatment for Japanese patients with hepatic encephalopathy
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology Research"
DOI: 10.1111/hepr.13415
Abstract: Rifaximin (RFX) improves hepatic encephalopathy (HE). However, information on long‐term treatment with RFX is limited. In this study, we aimed to investigate the effect of long‐term treatment with RFX on HE and liver function. Moreover,… read more here.
Keywords: long term; rfx; treatment; hepatic encephalopathy ... See more keywords
Rifaximin exerts beneficial effects in PI-IBS mouse model beyond gut microbiota
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.13841
Abstract: Background and aims Rifaximin is a minimally absorbed antibiotic which has shown efficacy in irritable bowel syndrome (IBS) patients. However, the mechanism how it effects in IBS is still incompletely defined. In this study, we… read more here.
Keywords: model; mouse model; rifaximin; ibs mouse ... See more keywords
Role of rifaximin in the management of alcohol‐associated hepatitis: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.16179
Abstract: Alcohol‐associated hepatitis (AAH) is an acute, inflammatory liver disease with severe short‐term and long‐term morbidity and mortality. AAH can lead to severe complications including hepatic failure, gastrointestinal bleeding, sepsis, and the development or decompensation of… read more here.
Keywords: associated hepatitis; review meta; role; systematic review ... See more keywords
Effect of rifaximin on infections, acute‐on‐chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA‐AH)
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DOI: 10.1111/liv.15207
Abstract: Alcoholic hepatitis (AH) is associated with a high incidence of infection and mortality. Rifaximin reduces bacterial overgrowth and translocation. We aimed to study whether the administration of rifaximin as an adjuvant treatment to corticosteroids decreases… read more here.
Keywords: effect rifaximin; rifaximin; mortality; alcoholic hepatitis ... See more keywords