Direct RIG‐I activation in human NK cells induces TRAIL‐dependent cytotoxicity toward autologous melanoma cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.31874
Abstract: Activation of the innate immune receptor retinoic acid‐inducible gene I (RIG‐I) by its specific ligand 5′‐triphosphate RNA (3pRNA) triggers anti‐tumor immunity, which is dependent on natural killer (NK) cell activation and cytokine induction. However, to… read more here.
Keywords: rig activation; rig; melanoma cells; activation ... See more keywords
Toll‐like receptors, long non‐coding RNA NEAT1, and RIG‐I expression are associated with HBeAg‐positive chronic hepatitis B patients in the active phase
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22886
Abstract: Innate immunity plays a crucial role in host‐virus interactions and greatly influences viral replication including HBV infection. However, few studies have investigated the possible antiviral immune roles played by TLRs, RIG‐I, and long no‐coding RNA… read more here.
Keywords: rna neat1; rig; hbeag positive; patients active ... See more keywords
Robust delivery of RIG‐I agonists using extracellular vesicles for anti‐cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12187
Abstract: Abstract The RIG‐I pathway can be activated by RNA containing 5′ triphosphate, leading to type I interferon release and immune activation. Hence, RIG‐I agonists have been used to induce immune responses against cancer as potential… read more here.
Keywords: extracellular vesicles; rig agonists; immunotherapy; delivery ... See more keywords
Evaluation of a calibration rig for stereo laparoscopes.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16310
Abstract: BACKGROUND Accurate camera and hand-eye calibration are essential to ensure high quality results in image guided surgery applications. The process must also be able to be undertaken by a non-expert user in a surgical setting. PURPOSE… read more here.
Keywords: calibration rig; tracked stereo; calibration; reconstruction ... See more keywords
RNA PAMPs as Molecular Tools for Evaluating RIG-I Function in Innate Immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7237-1_6
Abstract: Pathogen recognition receptors (PRR)s and their cognate pathogen-associated molecular pattern (PAMP) represent the basis of innate immune activation and immune response induction driven by the host-pathogen interaction that occurs during microbial infection in humans and… read more here.
Keywords: innate; molecular tools; rig; pamps molecular ... See more keywords
Innate immune response in patients with acute Zika virus infection
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00588-8
Abstract: Innate immunity receptors (Toll-like receptors/TLRs and RIG-like receptors/RLRs) are important for the initial recognition of Zika virus (ZIKV), modulation of protective immune response, and IFN-α and IFN-β production. Immunological mechanisms involved in protection or pathology… read more here.
Keywords: innate; rig; ifn; infection ... See more keywords
Locally analytic representations in the étale coverings of the Lubin-Tate moduli space
Sign Up to like & getrecommendations! Published in 2020 at "Israel Journal of Mathematics"
DOI: 10.1007/s11856-020-2059-z
Abstract: The Lubin-Tate moduli space $X_{0}^{\text{rig}}$ is a $p$-adic analytic open unit polydisc which parametrizes deformations of a formal group $H_{0}$ of finite height defined over an algebraically closed field of characteristic $p$. It is known… read more here.
Keywords: tate moduli; mathrm rig; lubin tate; rig ... See more keywords
Properties of Drillstring Vibration Absorber for Rotary Drilling Rig
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal for Science and Engineering"
DOI: 10.1007/s13369-020-04562-y
Abstract: During drilling into hard rocks, the vibration of telescopic drillstring for the rotary drilling rig becomes more severe, which not only leads to the fracture of drillstring, but also reduces the rock-breaking efficiency, the service… read more here.
Keywords: rig; drilling rig; rotary drilling; vibration ... See more keywords
Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.03.017
Abstract: The conventional view posits that E3 ligases function primarily through conjugating ubiquitin (Ub) to their substrate molecules. We report here that RIPLET, an essential E3 ligase in antiviral immunity, promotes the antiviral signaling activity of… read more here.
Keywords: immunity; rig; dependent independent; ubiquitin dependent ... See more keywords
Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2018.08.004
Abstract: Retinoic acid-inducible gene I (RIG-I) detects viral RNAs and induces antiviral responses. During viral RNA recognition by RIG-I, tripartite motif protein 25 (TRIM25) plays a critical regulatory role by inducing K63-linked RIG-I polyubiquitination. Previous proteomics… read more here.
Keywords: regulatory role; rig; tyrosine phosphorylation; src ... See more keywords
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109272
Abstract: SUMMARY The type I interferon (IFN) pathway is a key component of innate immune response upon invasion of foreign pathogens. It is also under precise control to prevent excessive upregulation and undesired inflammation cascade. In… read more here.
Keywords: rig; ifn; riok3; immune response ... See more keywords